Literature DB >> 720484

Radioimmunological determination of prostaglandin D2 synthesis in human thrombocytes.

H Anhut, B A Peskar, W Wachter, B Gräbling, B M Peskar.   

Abstract

A specific radioimmunoassay for prostaglandin D2 was developed. Using the radioimmunoassay, prostaglandin D2 synthesis by human thrombocytes was measured. While the cyclooxygenase inhibitor indomethacin inhibits formation of prostaglandin D2, increased formation of prostaglandin D2 was observed in the presence of the thromboxane synthetase inhibitor imidazole.

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Year:  1978        PMID： 720484     DOI： 10.1007/bf01932373

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  22 in total

1.  Effects of PGD2 on canine renal function.

Authors:  P M Bolger; G M Eisner; P T Shea; P W Ramwell; L M Slotkoff
Journal:  Nature       Date:  1977-06-16       Impact factor: 49.962

2.  Radioimmunological determination of thromboxane release in cardiac anaphylaxis.

Authors:  H Anhut; W Bernauer; B A Peskar
Journal:  Eur J Pharmacol       Date:  1977-07-01       Impact factor: 4.432

3.  Synthesis of prostaglandin D2 and thromboxane B2 by human platelets.

Authors:  M Ali; A L Cerskus; J Zamecnik; J W McDonald
Journal:  Thromb Res       Date:  1977-10       Impact factor: 3.944

4.  Prostaglandin D2 inhibits the aggregation of human platelets.

Authors:  J B Smith; M J Silver; C M Ingerman; J J Kocsis
Journal:  Thromb Res       Date:  1974-09       Impact factor: 3.944

5.  The effect of imidazole on human platelet aggregation.

Authors:  J W Davis; P E Phillips
Journal:  Blood       Date:  1971-10       Impact factor: 22.113

6.  Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions.

Authors:  P Needleman; B Bryan; A Wyche; S D Bronson; K Eakins; J A Ferrendelli; M Minkes
Journal:  Prostaglandins       Date:  1977-11

7.  Prostaglandin D2 (PGD2)--a potent coronary vasoconstrictor agent in the guinea pig isolated heart.

Authors:  K Schrör
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-03       Impact factor: 3.000

8.  Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis.

Authors:  M Hamberg; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

9.  Biosynthesis of prostaglandin D2. 1. Formation of prostaglandin D2 by human platelets.

Authors:  O Oelz; R Oelz; H R Knapp; B J Sweetman; J A Oates
Journal:  Prostaglandins       Date:  1977-02

10.  Imidazole: a selective inhibitor of thromboxane synthetase.

Authors:  S Moncada; S Bunting; K Mullane; P Thorogood; J R Vane; A Raz; P Needleman
Journal:  Prostaglandins       Date:  1977-04
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  6 in total

1.  Alterations in eicosanoid composition during embryonic development in the chorioallantoic membrane of the American alligator (Alligator mississippiensis) and domestic chicken (Gallus gallus).

Authors:  Theresa M Cantu; John A Bowden; Jacob Scott; Jimena B Pérez-Viscasillas; Kevin Huncik; Matthew P Guillette; Louis J Guillette
Journal:  Gen Comp Endocrinol       Date:  2016-07-09       Impact factor: 2.822

2.  Prostaglandin D2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in the chicken.

Authors:  H Anhut; K Brune; J C Frölich; B A Peskar
Journal:  Br J Pharmacol       Date:  1979-03       Impact factor: 8.739

3.  Release of 15-keto-13, 14-dihydro-thromboxane B2 and prostaglandin D2 during anaphylaxis as measured by radioimmunoassay.

Authors:  H Anhut; B A Peskar; W Bernauer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-12       Impact factor: 3.000

4.  The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels.

Authors:  U Förstermann; G Hertting; B Neufang
Journal:  Br J Pharmacol       Date:  1984-04       Impact factor: 8.739

5.  P2-purinoceptor induced prostaglandin synthesis in primary rat astrocyte cultures.

Authors:  P J Gebicke-Haerter; S Wurster; A Schobert; G Hertting
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-12       Impact factor: 3.000

6.  Effects of intracerebroventricular administration of prostaglandin D2 on behaviour, blood pressure and body temperature as compared to prostaglandins E2 and F2 alpha.

Authors:  U Förstermann; R Heldt; G Hertting
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
  6 in total

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