Literature DB >> 7106618

Impaired acetaldehyde oxidation in alcoholics.

K R Palmer, W J Jenkins.   

Abstract

High blood acetaldehyde levels in alcoholics after ethanol ingestion are due to reduced acetaldehyde oxidation rather than to an increased rate of its formation from ethanol. This is associated with low hepatic acetaldehyde dehydrogenase activity in alcoholic subjects and may represent a specific abnormality in them.

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Year:  1982        PMID： 7106618      PMCID： PMC1419765          DOI： 10.1136/gut.23.9.729

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  23 in total

1.  Effect of acetaldehyde on fatty acid oxidation and ketogenesis by hepatic mitochondria.

Authors:  A I Cederbaum; C S Lieber; E Rubin
Journal:  Arch Biochem Biophys       Date:  1975-07       Impact factor: 4.013

2.  High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects.

Authors:  M A Korsten; S Matsuzaki; L Feinman; C S Lieber
Journal:  N Engl J Med       Date:  1975-02-20       Impact factor: 91.245

3.  Acetaldehyde oxidation by hepatic mitochondria: decrease after chronic ethanol consumption.

Authors:  Y Hasumura; R Teschke; C S Lieber
Journal:  Science       Date:  1975-08-29       Impact factor: 47.728

4.  Liver aldehyde and alcohol dehydrogenase activities in rat strains genetically selected for their ethanol preference.

Authors:  T Koivula; M Koivusalo; K O Lindros
Journal:  Biochem Pharmacol       Date:  1975-10-01       Impact factor: 5.858

5.  Aldehyde dehydrogenase and ethanol preference in mice.

Authors:  J R Sheppard; P Albersheim; G Mcclearn
Journal:  J Biol Chem       Date:  1970-06-10       Impact factor: 5.157

6.  Influence of alcohol intake, length of abstinence and meprobamate on the rate of ethanol metabolism in man.

Authors:  G Ugarte; T Pereda; M E Pino; H Iturriaga
Journal:  Q J Stud Alcohol       Date:  1972-09

7.  Differences in the rate of ethanol metabolism in recently drinking alcoholic and nondrinking subjects.

Authors:  R M Kater; N Carulli; F L Iber
Journal:  Am J Clin Nutr       Date:  1969-12       Impact factor: 7.045

8.  Alcohol, amines, and alkaloids: a possible biochemical basis for alcohol addiction.

Authors:  V E Davis; M J Walsh
Journal:  Science       Date:  1970-02-13       Impact factor: 47.728

9.  Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference.

Authors:  C J Eriksson
Journal:  Biochem Pharmacol       Date:  1973-09-15       Impact factor: 5.858

10.  Rate-limiting factors in the oxidation of ethanol by isolated rat liver cells.

Authors:  A J Meijer; G M van Woerkom; J R Williamson; J M Tager
Journal:  Biochem J       Date:  1975-08       Impact factor: 3.857
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  8 in total

1.  Alcoholic liver disease in the 1980s.

Authors:  J B Saunders
Journal:  Br Med J (Clin Res Ed)       Date:  1983-12-17

2.  Development of hypoxemia in alcoholic liver disease.

Authors:  Shigeo Maruyama; Chisato Hirayama; Kazunori Maeda; Satoru Yamamoto; Masaharu Koda; Akihide Udagawa; Masayuki Inoue; Kensuke Umeki
Journal:  Dig Dis Sci       Date:  2005-02       Impact factor: 3.199

3.  Inhibition of erythrocyte aldehyde dehydrogenase activity and elimination kinetics of diethyldithiocarbamic acid methyl ester and its monothio analogue after administration of single and repeated doses of disulfiram to man.

Authors:  B Johansson; Z Stankiewicz
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

4.  Impaired acetaldehyde metabolism in patients with non-alcoholic liver disorders.

Authors:  K Matthewson; H Al Mardini; K Bartlett; C O Record
Journal:  Gut       Date:  1986-07       Impact factor: 23.059

5.  Ethanol metabolism in the generation of new antigenic determinants on liver cells.

Authors:  I R Crossley; J Neuberger; M Davis; R Williams; A L Eddleston
Journal:  Gut       Date:  1986-02       Impact factor: 23.059

6.  Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping.

Authors:  Ikuo Aoyama; Shinya Ohashi; Yusuke Amanuma; Kenshiro Hirohashi; Ayaka Mizumoto; Makiko Funakoshi; Mihoko Tsurumaki; Yukie Nakai; Katsuyuki Tanaka; Mariko Hanada; Aki Uesaka; Tsutomu Chiba; Manabu Muto
Journal:  Clin Transl Gastroenterol       Date:  2017-06-08       Impact factor: 4.488

7.  Ethanol Sensitization during Adolescence or Adulthood Induces Different Patterns of Ethanol Consumption without Affecting Ethanol Metabolism.

Authors:  Priscila F Carrara-Nascimento; Lucas B Hoffmann; Marcos B Contó; Tania Marcourakis; Rosana Camarini
Journal:  Front Behav Neurosci       Date:  2017-03-23       Impact factor: 3.558

Review 8.  Pathophysiological Aspects of Alcohol Metabolism in the Liver.

Authors:  Jeongeun Hyun; Jinsol Han; Chanbin Lee; Myunghee Yoon; Youngmi Jung
Journal:  Int J Mol Sci       Date:  2021-05-27       Impact factor: 5.923
  8 in total

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