Literature DB >> 7089572

Genetic length of a human chromosomal segment measured by recombination between two fragile sites.

G R Sutherland, E Baker, J C Mulley.   

Abstract

Two families were studied in which the same homolog of chromosome pair 10 expressed both the fragile sites on the long (q) arm at 10q23 and 10q25. Recombination between the fragile sites was observed in 3 of the 27 offspring in whom it could occur. The genetic length of chromosome between the fragile sites was 11 female centimorgans within a 95 percent probability interval of 4 to 28 centimorgans. This estimate of genetic length is comparable to those obtained with other methods.

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Year:  1982        PMID： 7089572     DOI： 10.1126/science.7089572

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Different inducibility and possible significance of several concomitant "fragile sites" in two brothers.

Authors:  F Shabtai; J Orlin; J Hart; I Halbrecht; D Klar; J Friedman
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132

2.  Mapping the human alpha globin gene complex to 16p13.2----pter.

Authors:  R N Simmers; J C Mulley; V J Hyland; D F Callen; G R Sutherland
Journal:  J Med Genet       Date:  1987-12       Impact factor: 6.318

3.  Regional localization for HLA by recombination with a fragile site at 6p23.

Authors:  J C Mulley; J Hay; L J Sheffield; G R Sutherland
Journal:  Am J Hum Genet       Date:  1983-11       Impact factor: 11.025

4.  A search for linkage in families with fragile sites.

Authors:  J C Mulley; C Nicholls; G R Sutherland
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

5.  Fra(10)(q25): the BrdU effect is substitution-dependent.

Authors:  S M Gollin; G P Holmquist; D H Ledbetter
Journal:  Am J Hum Genet       Date:  1985-01       Impact factor: 11.025

6.  Localization of the human RGR opsin gene to chromosome 10q23.

Authors:  X N Chen; J R Korenberg; M Jiang; D Shen; H K Fong
Journal:  Hum Genet       Date:  1996-06       Impact factor: 4.132
  6 in total

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