Literature DB >> 8641686

Localization of the human RGR opsin gene to chromosome 10q23.

X N Chen1, J R Korenberg, M Jiang, D Shen, H K Fong.   

Abstract

The human RGR gene encodes an opsin protein (retinal G protein-coupled receptor), which is expressed in Müller cells and the retinal pigment epithelium and is thought to play a role in the visual process. To investigate a possible linkage of the RGR gene to retinal dystrophies, the locus of the gene was mapped on human metaphase chromosomes. Genomic and cDNA fragments of the human RGR gene were used as probes for fluorescence in situ hybridization. Analysis of the fluorescence signals on high-resolution banded chromosomes showed that the RGR gene is localized to human chromosome 10q23. This result now provides for the rapid analysis of this gene with respect to inherited diseases of the retina.

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Year:  1996        PMID： 8641686     DOI： 10.1007/bf02346179

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  21 in total

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Authors:  S Attard-Montalto; N Evans; R A Sherwood
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2.  Molecular genetics of inherited variation in human color vision.

Authors:  J Nathans; T P Piantanida; R L Eddy; T B Shows; D S Hogness
Journal:  Science       Date:  1986-04-11       Impact factor: 47.728

3.  Assignment of the rhodopsin gene to human chromosome three, region 3q21-3q24 by in situ hybridization studies.

Authors:  R S Sparkes; I Klisak; D Kaufman; T Mohandas; A J Tobin; J F McGinnis
Journal:  Curr Eye Res       Date:  1986-10       Impact factor: 2.424

4.  An opsin homologue in the retina and pigment epithelium.

Authors:  M Jiang; S Pandey; H K Fong
Journal:  Invest Ophthalmol Vis Sci       Date:  1993-12       Impact factor: 4.799

5.  Chromosomal organization of adrenergic receptor genes.

Authors:  T L Yang-Feng; F Y Xue; W W Zhong; S Cotecchia; T Frielle; M G Caron; R J Lefkowitz; U Francke
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

6.  Regional mapping of RBP4 to 10q23----q24 and RBP1 to 3q21----q22 in man.

Authors:  M Rocchi; A Covone; G Romeo; R Faraonio; V Colantuoni
Journal:  Somat Cell Mol Genet       Date:  1989-03

7.  A human opsin-related gene that encodes a retinaldehyde-binding protein.

Authors:  D Shen; M Jiang; W Hao; L Tao; M Salazar; H K Fong
Journal:  Biochemistry       Date:  1994-11-08       Impact factor: 3.162

8.  Human interstitial retinol-binding protein (IRBP): cloning, partial sequence, and chromosomal localization.

Authors:  G I Liou; S L Fong; J Gosden; P van Tuinen; D H Ledbetter; S Christie; D Rout; S Bhattacharya; R G Cook; Y Li
Journal:  Somat Cell Mol Genet       Date:  1987-07

9.  Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24.

Authors:  L A Cannizzaro; M M Aronson; H J Thiesen
Journal:  Hum Genet       Date:  1993-05       Impact factor: 4.132

10.  The distribution of retinol-binding protein and its mRNA in the rat eye.

Authors:  J Herbert; T Cavallaro; R Martone
Journal:  Invest Ophthalmol Vis Sci       Date:  1991-02       Impact factor: 4.799
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  6 in total

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2.  Prioritization of retinal disease genes: an integrative approach.

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Review 3.  A novel cone visual cycle in the cone-dominated retina.

Authors:  Albert Muniz; Elia T Villazana-Espinoza; Andrea L Hatch; Simon G Trevino; Donald M Allen; Andrew T C Tsin
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Review 4.  The Role of Vitamin A in Retinal Diseases.

Authors:  Jana Sajovic; Andrej Meglič; Damjan Glavač; Špela Markelj; Marko Hawlina; Ana Fakin
Journal:  Int J Mol Sci       Date:  2022-01-18       Impact factor: 5.923

5.  Expression of Retinal G Protein-Coupled Receptor, a Member of the Opsin Family, in Human Skin Cells and Its Mediation of the Cellular Functions of Keratinocytes.

Authors:  Yangguang Gu; Yu Wang; Yinghua Lan; Jianglong Feng; Wen Zeng; Wei Zhang; Hongguang Lu
Journal:  Front Cell Dev Biol       Date:  2022-04-04

6.  Clinical Features of a Retinopathy Associated With a Dominant Allele of the RGR Gene.

Authors:  Rola Ba-Abbad; Monique Leys; Xinjing Wang; Christina Chakarova; Naushin Waseem; Keren J Carss; F Lucy Raymond; Kinga M Bujakowska; Eric A Pierce; Omar A Mahroo; Moin D Mohamed; Graham E Holder; Marybeth Hummel; Gavin Arno; Andrew R Webster
Journal:  Invest Ophthalmol Vis Sci       Date:  2018-10-01       Impact factor: 4.799
  6 in total

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