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Literature DB >> 6973607

Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses.

Abstract

We have described a model system in which helper T cells are required to mount a primary antiviral cytolytic T lymphocyte response. The radioresistant helper cell can be found in the spleens of mice that have been immunized subcutaneously with influenza viruses 6-8 d previously. These helper cells appear to be type specific but cross-reactive among the subtypes of influenza A viruses. The phenotypes of the interacting cell populations were determined.

Entities: Species

Mesh：

Substances：
Antigens, Viral

Year: 1981 PMID： 6973607 PMCID： PMC2186412 DOI： 10.1084/jem.154.2.541

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

16 in total

1. Cytotoxic T cells specific for influenza virus-infected target cells.

Authors: K L Yap; G L Ada
Journal: Immunology Date: 1977-02 Impact factor: 7.397

2. Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes.

Authors: T J Braciale
Journal: Cell Immunol Date: 1977-10 Impact factor: 4.868

3. Cytotoxic T cells to type A influenza virus; viral hemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity.

Authors: H J Zweerink; B A Askonas; D Millican; S A Courtneidge; J J Skehel
Journal: Eur J Immunol Date: 1977-09 Impact factor: 5.532

4. Induction and characterization of delayed-type hypersensitivity to influenza virus in mice.

Authors: F Y Liew; S M Russell; C M Brand
Journal: Eur J Immunol Date: 1979-10 Impact factor: 5.532

5. A T helper cell for anti-viral cytotoxic T-cell responses.

Authors: R B Ashman; A Müllbacher
Journal: J Exp Med Date: 1979-11-01 Impact factor: 14.307

6. Immunologic recognition of influenza virus-infected cells. II. Expression of influenza A matrix protein on the infected cell surface and its role in recognition by cross-reactive cytotoxic T cells.

Authors: T J Braciale
Journal: J Exp Med Date: 1977-09-01 Impact factor: 14.307

7. The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

Authors: R M Zinkernagel; G N Callahan; A Althage; S Cooper; J W Streilein; J Klein
Journal: J Exp Med Date: 1978-03-01 Impact factor: 14.307

8. Generation of both cross-reactive and virus-specific T-cell populations after immunization with serologically distinct influenza A viruses.

Authors: R B Effros; P C Doherty; W Gerhard; J Bennink
Journal: J Exp Med Date: 1977-03-01 Impact factor: 14.307

9. Specificity of cytotoxicity T cells directed to influenza virus hemagglutinin.

Authors: T J Braciale
Journal: J Exp Med Date: 1979-04-01 Impact factor: 14.307

10. Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses.

Authors: W E Biddison; P C Doherty; R G Webster
Journal: J Exp Med Date: 1977-09-01 Impact factor: 14.307

5 in total

1. Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model.

Authors: S C Gupta; H Hengartner; R M Zinkernagel
Journal: Proc Natl Acad Sci U S A Date: 1986-04 Impact factor: 11.205

2. Enumeration of viral antigen-reactive helper T lymphocytes in human peripheral blood by limiting dilution for analysis of viral antigen-reactive T-cell pools in virus-seropositive and virus-seronegative individuals.

Authors: K A Clouse; P W Adams; C G Orosz
Journal: J Clin Microbiol Date: 1989-10 Impact factor: 5.948