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Literature DB >> 227982

A T helper cell for anti-viral cytotoxic T-cell responses.

Abstract

We demonstrate here: (a) the existence of T helper (Th) cells that augment the generation of virus-specific cytotoxic T cells in vitro, (b) that the helper cells carry the theta and Ly 1 membrane antigens, (c) that activation of the Th effect is specific for viral antigens, and (d) that the delivery of help is not H-2 restricted.

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Substances：

Year: 1979 PMID： 227982 PMCID： PMC2185695 DOI： 10.1084/jem.150.5.1277

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

13 in total

1. Different rules govern help for cytotoxic T cells and B cells.

Authors: J R Bennink; P C Doherty
Journal: Nature Date: 1978 Dec 21-28 Impact factor: 49.962

2. Requirements for stimulation of T cell responses against virus-infected cells: nature of ectromelia virus-infected cells capable of stimulating cytotoxic T cells in a secondary response in vitro.

Authors: T Pang; R V Blanden
Journal: Aust J Exp Biol Med Sci Date: 1977-10

3. Genetic factors in the stimulation of T cell responses against ectromelia virus-infected cells: role of H-2K, H-2D, and H-2I genes.

Authors: T Pang; R V Blanden
Journal: Aust J Exp Biol Med Sci Date: 1977-10

4. Cytotoxic T cells specific for influenza virus-infected target cells.

Authors: K L Yap; G L Ada
Journal: Immunology Date: 1977-02 Impact factor: 7.397

5. Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

Authors: H von Boehmer; W Haas; N K Jerne
Journal: Proc Natl Acad Sci U S A Date: 1978-05 Impact factor: 11.205

6. Cooperation between mouse T-cell subpopulations in the cell-mediated response to a natural poxvirus pathogen.

Authors: T Pang; I F McKenzie; R V Blanden
Journal: Cell Immunol Date: 1976-10 Impact factor: 4.868

7. Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex.

Authors: J Sprent
Journal: J Exp Med Date: 1978-04-01 Impact factor: 14.307

8. The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

Authors: R M Zinkernagel; G N Callahan; A Althage; S Cooper; J W Streilein; J Klein
Journal: J Exp Med Date: 1978-03-01 Impact factor: 14.307

9. A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors.

Authors: L M Pilarski
Journal: J Exp Med Date: 1977-03-01 Impact factor: 14.307

10. Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. I. Failure to collaborate with B cells of the opposite parental strain not associated with active suppression.

Authors: J Sprent
Journal: J Exp Med Date: 1978-04-01 Impact factor: 14.307

25 in total

1. Activated B cells can deliver help for the in vitro generation of antiviral cytotoxic T cells.

Authors: Y Liu; A Müllbacher
Journal: Proc Natl Acad Sci U S A Date: 1989-06 Impact factor: 11.205

Review 2. T cell subsets participating in the generation of cytotoxic T cells.

Authors: M M Simon; K Eichmann
Journal: Springer Semin Immunopathol Date: 1980-05

3. Administration of superantigens protects mice from lethal Listeria monocytogenes infection by enhancing cytotoxic T cells.

Authors: S Okamoto; S Kawabata; I Nakagawa; S Hamada
Journal: Infect Immun Date: 2001-11 Impact factor: 3.441

A T helper cell for anti-viral cytotoxic T-cell responses.

1. Different rules govern help for cytotoxic T cells and B cells.

2. Requirements for stimulation of T cell responses against virus-infected cells: nature of ectromelia virus-infected cells capable of stimulating cytotoxic T cells in a secondary response in vitro.

3. Genetic factors in the stimulation of T cell responses against ectromelia virus-infected cells: role of H-2K, H-2D, and H-2I genes.

4. Cytotoxic T cells specific for influenza virus-infected target cells.

5. Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

6. Cooperation between mouse T-cell subpopulations in the cell-mediated response to a natural poxvirus pathogen.

7. Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex.

8. The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

9. A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors.

10. Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. I. Failure to collaborate with B cells of the opposite parental strain not associated with active suppression.

1. Activated B cells can deliver help for the in vitro generation of antiviral cytotoxic T cells.

Review 2. T cell subsets participating in the generation of cytotoxic T cells.

3. Administration of superantigens protects mice from lethal Listeria monocytogenes infection by enhancing cytotoxic T cells.

4. Host-damaging immune responses in virus infections.

5. Persistence of cell-mediated immunity to influenza A virus in mice.

6. Recent developments in immunovirology.

7. Analysis of haplotype preference in the cytotoxic T-cell response to H-Y.

8. Rescue of anti-influenza A virus cytotoxic T-lymphocyte responses in chemotherapy-suppressed mice.

9. Cytotoxic T-memory cells in virus infection and the specificity of helper T cells.

10. The human cytotoxic T cell response to influenza A vaccination.