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Literature DB >> 6956884

Differential expression of selected genes in human leukemia leukocytes.

Abstract

cDNA clones complementary to mRNA of cells from patients having chronic lymphocytic leukemia (CLL) were used to examine quantitative changes in the mRNA levels of specific genes in human leukemia leukocytes. Fourteen (of 400) CLL-positive clones that did not hybridize with placental mRNA were studied. Three of the 14 clones were highly represented in mRNA from CEM, a T-cell line. One clone was highly represented in mRNA from CLL and two were highly represented in mRNA from patients with chronic myelocytic leukemia. Ten clones were not significantly represented in normal leukocytes and spleen mRNA. We have identified several genes that are differentially expressed in human leukemia leukocytes.

Entities: Disease Species

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Year: 1982 PMID： 6956884 PMCID： PMC346737 DOI： 10.1073/pnas.79.15.4668

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

27 in total

1. New features of the regulation of the tryptophan operon.

Authors: K Bertrand; L Korn; F Lee; T Platt; C L Squires; C Squires; C Yanofsky
Journal: Science Date: 1975-07-04 Impact factor: 47.728

2. Abundancy and diversity of mRNA sequences in human leukocytes.

Authors: M T Kuo; M E Ried; G F Saunders
Journal: Differentiation Date: 1976-06-04 Impact factor: 3.880

3. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

4. Processing of the major leftward mRNA of coliphage lambda.

Authors: H A Lozeron; J E Dahlberg; W Szybalski
Journal: Virology Date: 1976-05 Impact factor: 3.616

5. Structural gene sets active in embryos and adult tissues of the sea urchin.

Authors: G A Galau; W H Klein; M M Davis; B J Wold; R J Britten; E H Davidson
Journal: Cell Date: 1976-04 Impact factor: 41.582

6. Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells.

Authors: M Dagert; S D Ehrlich
Journal: Gene Date: 1979-05 Impact factor: 3.688

Review 7. Irreversible gene repression model for control of development.

Authors: A I Caplan; C P Ordahl
Journal: Science Date: 1978-07-14 Impact factor: 47.728

8. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors: P S Thomas
Journal: Proc Natl Acad Sci U S A Date: 1980-09 Impact factor: 11.205

9. Gene expression in normal and neoplastic mammary tissue.

Authors: S C Supowit; J M Rosen
Journal: Biochemistry Date: 1980-07-22 Impact factor: 3.162

10. Extensive homology of nuclear ribonucleic acid and polysomal poly(adenylic acid) messenger ribonucleic acid between normal and neoplastically transformed cells.

Authors: R K Moyzis; D L Grady; D W Li; S E Mirvis; P O Ts'o
Journal: Biochemistry Date: 1980-03-04 Impact factor: 3.162

8 in total

1. Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues.

Authors: T M Gress; J D Hoheisel; G G Lennon; G Zehetner; H Lehrach
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

2. Molecular hybridization studies with scrapie brain nucleic acids. II. Differential expression in scrapie hamster brain.

Authors: T Borrás; J J Merendino; C J Gibbs
Journal: Arch Virol Date: 1986 Impact factor: 2.574

Differential expression of selected genes in human leukemia leukocytes.

1. New features of the regulation of the tryptophan operon.

2. Abundancy and diversity of mRNA sequences in human leukocytes.

3. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

4. Processing of the major leftward mRNA of coliphage lambda.

5. Structural gene sets active in embryos and adult tissues of the sea urchin.

6. Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells.

Review 7. Irreversible gene repression model for control of development.

8. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

9. Gene expression in normal and neoplastic mammary tissue.

10. Extensive homology of nuclear ribonucleic acid and polysomal poly(adenylic acid) messenger ribonucleic acid between normal and neoplastically transformed cells.

1. Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues.

2. Molecular hybridization studies with scrapie brain nucleic acids. II. Differential expression in scrapie hamster brain.

3. Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.

4. Lineage-specific and differentiation-stage-specific gene expression in normal and leukaemic human myeloid cells.

5. Cloning of sequences expressed specifically in tumors of rat.

6. A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2.

7. Characterisation of a messenger RNA selectively expressed in human breast cancer.

8. Preferentially expressed genes in stomach adenocarcinoma cells.