Literature DB >> 3426917

Preferentially expressed genes in stomach adenocarcinoma cells.

T Shiosaka1, Y Tanaka, Y Kobayashi.   

Abstract

cDNA clones complementary to mRNA of neoplastic cells of human stomach tissue were used to examine quantitative changes in the mRNA levels of specific genes in neoplastic cells. Poly(A)+ RNA from poorly differentiated adenocarcinoma cells of a female patient with stomach cancer was used for construction of a complementary DNA (cDNA) library. Screening of the 18,000 colonies utilizing 32P-cDNAs derived from normal human tissue and stomach carcinoma tissue samples was used to select clones likely to represent sequences preferentially expressed in stomach carcinoma cells. Twenty-six recombinants were initially selected and further analysis of these clones indicated that eight (4-3D, 9-2D, 9-4G, 29-1G, 29-6F, 37-1B, 115-5A and 52-5F) contain sequences preferentially expressed in stomach carcinoma cells. We have identified the 9-4G, 29-1A, and 29-6F genes which are differentially expressed in human neoplasia.

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Year:  1987        PMID： 3426917      PMCID： PMC2001899          DOI： 10.1038/bjc.1987.239

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  29 in total

1.  Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells.

Authors:  M Dagert; S D Ehrlich
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Authors:  P S Thomas
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3.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.

Authors:  W S Hayward; B G Neel; S M Astrin
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

4.  Activation of cellular genes by avian RNA tumor viruses.

Authors:  M Groudine; H Weintraub
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5.  The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers.

Authors:  J Vieira; J Messing
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

6.  Expression of a cellular oncogene during liver regeneration.

Authors:  M Goyette; C J Petropoulos; P R Shank; N Fausto
Journal:  Science       Date:  1983-02-04       Impact factor: 47.728

7.  Sea urchin embryo mRNA sequences expressed in the nuclear RNA of adult tissues.

Authors:  B J Wold; W H Klein; B R Hough-Evans; R J Britten; E H Davidson
Journal:  Cell       Date:  1978-08       Impact factor: 41.582

8.  Transcriptional control in the production of liver-specific mRNAs.

Authors:  E Derman; K Krauter; L Walling; C Weinberger; M Ray; J E Darnell
Journal:  Cell       Date:  1981-03       Impact factor: 41.582

9.  Differential expression of selected genes in human leukemia leukocytes.

Authors:  T Shiosaka; G F Saunders
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

10.  Insulin gene expression during development of the fetal bovine pancreas.

Authors:  M L Frazier; R A Montagna; G F Saunders
Journal:  Biochemistry       Date:  1981-01-20       Impact factor: 3.162
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  2 in total

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Authors:  T M Gress; J D Hoheisel; G G Lennon; G Zehetner; H Lehrach
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2.  Characterisation of a messenger RNA selectively expressed in human breast cancer.

Authors:  R A Skilton; Y A Luqmani; R A McClelland; R C Coombes
Journal:  Br J Cancer       Date:  1989-08       Impact factor: 7.640
  2 in total

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