Literature DB >> 3001652

Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.

J Kudo, L Y Chao, F Narni, G F Saunders.   

Abstract

The primary structures of a cDNA and the genomic DNA of a gene selectively expressed in chronic lymphocytic leukemia were determined. A computer search of the nucleotide sequence data bank identified this gene as the invariant gamma-chain associated with class II histocompatibility antigens. The invariant gamma-chain genomic sequence spans about 11 kilobases, with eight exons and seven introns. Three of the introns contain members of the Alu repeat family. A putative cap site and promoter sequence were identified at the 5' end of the gene. One or two copies of the gene is present in each haploid genome, and no evidence for amplification or polymorphism was obtained.

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Year:  1985        PMID： 3001652      PMCID： PMC318954          DOI： 10.1093/nar/13.24.8827

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  38 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

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Review 3.  Transcription termination and 3' processing: the end is in site!

Authors:  M L Birnstiel; M Busslinger; K Strub
Journal:  Cell       Date:  1985-06       Impact factor: 41.582

4.  Detection of a common polypeptide chain in I--A and I--E sub-region immunoprecipitates.

Authors:  P P Jones; D B Murphy; D Hewgill; H O McDevitt
Journal:  Mol Immunol       Date:  1979-01       Impact factor: 4.407

Review 5.  In search of a function for the invariant chain associated with Ia antigens.

Authors:  E O Long
Journal:  Surv Immunol Res       Date:  1985

6.  Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro.

Authors:  B Ruskin; A R Krainer; T Maniatis; M R Green
Journal:  Cell       Date:  1984-08       Impact factor: 41.582

7.  The isolation of structural genes from libraries of eucaryotic DNA.

Authors:  T Maniatis; R C Hardison; E Lacy; J Lauer; C O'Connell; D Quon; G K Sim; A Efstratiadis
Journal:  Cell       Date:  1978-10       Impact factor: 41.582

8.  Isolation of high-molecular-weight DNA from mammalian cells.

Authors:  M Gross-Bellard; P Oudet; P Chambon
Journal:  Eur J Biochem       Date:  1973-07-02

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

Authors:  E O Long; C T Wake; J Gorski; B Mach
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
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  15 in total

1.  Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation.

Authors:  D M O'Sullivan; D Noonan; V Quaranta
Journal:  J Exp Med       Date:  1987-08-01       Impact factor: 14.307

2.  The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.

Authors:  M Jacob; H Gallinaro
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971

3.  Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.

Authors:  C Doyle; P J Ford; P D Ponath; T Spies; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

4.  Tumor necrosis factor alpha regulates expression of the major histocompatibility complex class II-associated invariant chain by binding of an NF-kappa B-like factor to a promoter element.

Authors:  U Pessara; N Koch
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

5.  Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.

Authors:  D M O'Sullivan; D Larhammar; M C Wilson; P A Peterson; V Quaranta
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

6.  Two distinct nuclear factors bind the conserved regulatory sequences of a rabbit major histocompatibility complex class II gene.

Authors:  N Sittisombut
Journal:  Mol Cell Biol       Date:  1988-05       Impact factor: 4.272

7.  Localization of the HLA class II-associated invariant chain gene to human chromosome band 5q32.

Authors:  M Genuardi; G F Saunders
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

8.  Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733.

Authors:  A J Linnenbach; J Wojcierowski; S A Wu; J J Pyrc; A H Ross; B Dietzschold; D Speicher; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

9.  Molecular cloning and expression of two chicken invariant chain isoforms produced by alternative splicing.

Authors:  Dalian Zhong; Weiyi Yu; Yuhua Liu; Jing Liu; Jinnian Li
Journal:  Immunogenetics       Date:  2004-11-16       Impact factor: 2.846

10.  Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits.

Authors:  A M Brown; M W Linhoff; B Stein; K L Wright; A S Baldwin; P V Basta; J P Ting
Journal:  Mol Cell Biol       Date:  1994-05       Impact factor: 4.272
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