Literature DB >> 6951505

In vitro activity of N-formimidoyl thienamycin and other beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus.

R L Thompson, K A Fisher, R P Wenzel.   

Abstract

Of 43 isolates of methicillin-resistant Staphylococcus aureus, 90% were inhibited by 8 micrograms or less of N-formimidoyl thienamycin per ml by the agar-dilution technique. Cefamandole, cefotaxime, cefoperazone, moxalactam, and cefsulodin showed relatively poor activity. Vancomycin was the most active compound by weight, inhibiting 93% of strains at 1 microgram/ml.

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Year:  1982        PMID: 6951505      PMCID: PMC181885          DOI: 10.1128/AAC.21.2.341

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  13 in total

1.  Methicillin-resistant Staphylococcus aureus at Boston City Hospital. Bacteriologic and epidemiologic observations.

Authors:  F F Barrett; R F McGehee; M Finland
Journal:  N Engl J Med       Date:  1968-08-29       Impact factor: 91.245

2.  Methicillin-resistant staphylococci.

Authors:  F H Kayser; T M Mak
Journal:  Am J Med Sci       Date:  1972-09       Impact factor: 2.378

3.  Antibiotic susceptibility testing by a standardized single disk method.

Authors:  A W Bauer; W M Kirby; J C Sherris; M Turck
Journal:  Am J Clin Pathol       Date:  1966-04       Impact factor: 2.493

4.  An outbreak of methicillin-resistant Staphylococcus aureus infection. Observations in hospital and nursing home.

Authors:  R D O'Toole; W L Drew; B J Dahlgren; H N Beaty
Journal:  JAMA       Date:  1970-07-13       Impact factor: 56.272

5.  Resistance of Staphylococcus aureus to semisynthetic penicillins and cephalothin.

Authors:  A S Richmond; M S Simberkoff; S Schaefler; J J Rahal
Journal:  J Infect Dis       Date:  1977-01       Impact factor: 5.226

6.  Antibacterial activity of a new 1-oxa cephalosporin compared with that of other beta-lactam compounds.

Authors:  H C Neu; N Aswapokee; K P Fu; P Aswapokee
Journal:  Antimicrob Agents Chemother       Date:  1979-08       Impact factor: 5.191

7.  Use of a heavy inoculum in the in vitro evaluation of the anti-staphylococcal activity of 19 cephalosporins.

Authors:  M Laverdiere; D Welter; L D Sabath
Journal:  Antimicrob Agents Chemother       Date:  1978-04       Impact factor: 5.191

8.  MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

Authors:  H Kropp; J G Sundelof; J S Kahan; F M Kahan; J Birnbaum
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191

9.  In vitro activity of N-formimidoyl thienamycin (MK0787), a crystalline derivative of thienamycin.

Authors:  V W Horadam; J D Smilack; C L Montgomery; J Werringloer
Journal:  Antimicrob Agents Chemother       Date:  1980-10       Impact factor: 5.191

10.  Antibacterial activities of a new stabilized thienamycin, N-formimidoyl thienamycin, in comparison with other antibiotics.

Authors:  T Kesado; T Hashizume; Y Asahi
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191

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  12 in total

1.  Failure of routine susceptibility tests to detect imipenem resistance among strains of methicillin-resistant Staphylococcus aureus.

Authors:  J M Boyce; E Papa; R Dickenson; A A Medeiros
Journal:  Antimicrob Agents Chemother       Date:  1991-07       Impact factor: 5.191

2.  Rationale for eliminating Staphylococcus breakpoints for β-lactam agents other than penicillin, oxacillin or cefoxitin, and ceftaroline.

Authors:  Jennifer Dien Bard; Janet A Hindler; Howard S Gold; Brandi Limbago
Journal:  Clin Infect Dis       Date:  2014-01-22       Impact factor: 9.079

3.  In vitro and in vivo study of fosfomycin in methicillin-resistant Staphylococcus aureus septicaemia.

Authors:  W Y Lau; C H Teoh-Chan; S T Fan; K F Lau
Journal:  J Hyg (Lond)       Date:  1986-06

4.  Vancomycin for treatment of infections with methicillin-resistant Staphylococcus aureus: are there alternatives?

Authors:  D Milatovic
Journal:  Eur J Clin Microbiol       Date:  1986-12       Impact factor: 3.267

5.  A prospective randomized trial of imipenem-cilastatin versus clindamycin/tobramycin in the treatment of intra-abdominal and pelvic infections.

Authors:  L A Mandell; P L Turgeon; A R Ronalds
Journal:  Can J Infect Dis       Date:  1993-09

6.  Activity of 18 antimicrobial agents against multi-resistant strains of Staphylococcus aureus isolated from intensive care patients.

Authors:  D Duncker; U Ullmann
Journal:  Infection       Date:  1985 Sep-Oct       Impact factor: 3.553

Review 7.  In vitro activity of imipenem--a review.

Authors:  I Braveny
Journal:  Eur J Clin Microbiol       Date:  1984-10       Impact factor: 3.267

8.  In vitro activities of teichomycin, fusidic acid, flucloxacillin, fosfomycin, and vancomycin against methicillin-resistant Staphylococcus aureus.

Authors:  S H Guenthner; R P Wenzel
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

9.  Subinhibitory concentrations of imipenem induce increased resistance to methicillin and imipenem in vitro in methicillin-resistant Staphylococcus aureus.

Authors:  B A Forbes; K D McClatchey; D R Schaberg
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191

10.  In vitro susceptibility patterns of methicillin-resistant and-susceptible Staphylococcus auerues strains in a population of parenteral drug abusers from 1972 to 1981.

Authors:  N Markowitz; D J Pohlod; L D Saravolatz; E L Quinn
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191

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