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Literature DB >> 3637200

In vitro and in vivo study of fosfomycin in methicillin-resistant Staphylococcus aureus septicaemia.

W Y Lau, C H Teoh-Chan, S T Fan, K F Lau.

Abstract

Five hundred strains of methicillin-resistant Staphylococcus aureus were tested against various anti-staphylococcal agents. Vancomycin, fusidic acid and fosfomycin were found to be the most effective. Only 1 strain out of 500 was resistant to fosfomycin. Three patients with methicillin-resistant Staphylococcus aureus septicaemia were successfully treated by fosfomycin. We conclude that fosfomycin could be the drug of choice for methicillin-resistant Staphylococcus aureus infection.

Entities: Chemical Disease Species

Mesh：

Substances：
Fosfomycin
Methicillin

Year: 1986 PMID： 3637200 PMCID： PMC2129703 DOI： 10.1017/s0022172400066183

Source DB: PubMed Journal: J Hyg (Lond) ISSN： 0022-1724

16 in total

1. Clinical pharmacology and in vitro activity of phosphonomycin.

Authors: D G Kestle; W M Kirby
Journal: Antimicrob Agents Chemother (Bethesda) Date: 1969

2. International collaborative study on standardization of bacterial sensitivity to fosfomycin.

Authors: J M Andrews; F Baquero; J M Beltran; E Canton; F Crokaert; M Gobernado; R Gomez-Ius; E Loza; M Navarro; T Olay
Journal: J Antimicrob Chemother Date: 1983-10 Impact factor: 5.790

3. Recent developments in the field of phosphonic acid antibiotics.

Authors: M Neuman
Journal: J Antimicrob Chemother Date: 1984-10 Impact factor: 5.790

4. The emergence of methicillin-resistant Staphylococcus aureus.

Authors: R P Wenzel
Journal: Ann Intern Med Date: 1982-09 Impact factor: 25.391

5. International recognition of methicillin-resistant strains of Staphylococcus aureus.

Authors: R L Thompson; R P Wenzel
Journal: Ann Intern Med Date: 1982-12 Impact factor: 25.391

6. In vitro activities of teichomycin, fusidic acid, flucloxacillin, fosfomycin, and vancomycin against methicillin-resistant Staphylococcus aureus.

Authors: S H Guenthner; R P Wenzel
Journal: Antimicrob Agents Chemother Date: 1984-08 Impact factor: 5.191

2. In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius.

Authors: Matthew DiCicco; Suresh Neethirajan; J Scott Weese; Ameet Singh
Journal: BMC Microbiol Date: 2014-05-19 Impact factor: 3.605

2 in total

In vitro and in vivo study of fosfomycin in methicillin-resistant Staphylococcus aureus septicaemia.

1. Clinical pharmacology and in vitro activity of phosphonomycin.

2. International collaborative study on standardization of bacterial sensitivity to fosfomycin.

3. Recent developments in the field of phosphonic acid antibiotics.

4. The emergence of methicillin-resistant Staphylococcus aureus.

5. International recognition of methicillin-resistant strains of Staphylococcus aureus.

6. In vitro activities of teichomycin, fusidic acid, flucloxacillin, fosfomycin, and vancomycin against methicillin-resistant Staphylococcus aureus.

7. Treatment of infections due to methicillin-resistant Staphylococcus aureus.

8. Community-acquired methicillin-resistant Staphylococcus aureus endocarditis in the Detroit Medical Center.

9. Activity of fosfomycin in the treatment of bacterial infections.

10. A general survey of antibiotic treatment of staphylococcal septicaemia and endocarditis.

1. Fosfomycin for the initial treatment of acute haematogenous osteomyelitis.

2. In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius.