Literature DB >> 6940196

Photoisomerized bilirubin in blood from infants receiving phototherapy.

A A Lamola, W E Blumberg, R McClead, A Fanaroff.   

Abstract

A pigment different from (Z,Z)bilirubin-IX alpha was detected by fluorometric methods in blood specimens from newborn infants undergoing blue-light therapy for unconjugated hyperbilirubinemia; it was not detected in specimens from infants not under therapy. The phototherapy-associated pigment has fluorescence, solubility, and photochemical properties that are identical to those exhibited by what are thought to be configurational (Z leads to E) isomers of bilirubin. It is concluded that isomerized bilirubin in the blood of neonates under phototherapy can reach as high as 15% of the total.

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Year:  1981        PMID： 6940196      PMCID： PMC319239          DOI： 10.1073/pnas.78.3.1882

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  Influence of phototherapy on the biliary bilirubin excretion pattern in newborn infants with hyperbilirubinemia.

Authors:  H T Lund; J Jacobsen
Journal:  J Pediatr       Date:  1974-08       Impact factor: 4.406

2.  Flurorometric study of the partition of bilirubin among blood components: basis for rapid microassays of bilirubin and bilirubin binding capacity in whole blood.

Authors:  A A Lamola; J Eisinger; W E Blumberg; S C Patel; J Flores
Journal:  Anal Biochem       Date:  1979-11-15       Impact factor: 3.365

3.  High-pressure liquid chromatographic analysis of anaerobic photoproducts of bilirubin-IX alpha in vitro and its comparison with photoproducts in vivo.

Authors:  S Onishi; N Kawade; S Itoh; K Isobe; S Sugiyama
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

4.  Demonstration of a geometric isomer of bilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant and the mechanism of jaundice phototherapy.

Authors:  S Onishi; K Isobe; S Itoh; N Kawade; S Sugiyama
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

5.  Wavelength dependence of bilirubin photoreactivity.

Authors:  D A Lightner; A Cu
Journal:  Life Sci       Date:  1977-02-15       Impact factor: 5.037

Review 6.  New concepts in phototherapy: photoisomerization of bilirubin IX alpha and potential toxic effects of light.

Authors:  A N Cohen; J D Ostrow
Journal:  Pediatrics       Date:  1980-04       Impact factor: 7.124

7.  A rapid fluorometric method for determining bilirubin levels and binding in the blood of neonates: comparisons with a diazo method and with 2-(4'-hydroxybenzene)azobenzoic acid dye binding.

Authors:  A K Brown; J Eisinger; W E Blumberg; J Flores; G Boyle; A A Lamola
Journal:  Pediatrics       Date:  1980-04       Impact factor: 7.124

8.  Rapid fluorometric assay of bilirubin and bilirubin binding capacity in blood of jaundiced neonates: comparisons with other methods.

Authors:  W J Cashore; W Oh; W E Blumberg; J Eisinger; A A Lamola
Journal:  Pediatrics       Date:  1980-09       Impact factor: 7.124

9.  Photocatabolism of labeled bilirubin in the congenitally jaundiced (Gunn) rat.

Authors:  J D Ostrow
Journal:  J Clin Invest       Date:  1971-03       Impact factor: 14.808

10.  Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning.

Authors:  W E Blumberg; J Eisinger; A A Lamola; D M Zuckerman
Journal:  J Lab Clin Med       Date:  1977-04
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  10 in total

1.  Early formation of bilirubin isomers during phototherapy for neonatal jaundice: effects of single vs. double fluorescent lamps vs. photodiodes.

Authors:  Khalaf Mreihil; Poul Madsen; Britt Nakstad; Jūratė Šaltytė Benth; Finn Ebbesen; Thor Willy Ruud Hansen
Journal:  Pediatr Res       Date:  2015-03-20       Impact factor: 3.756

2.  Interaction of bilirubin with human lymphocytes and granulocytes--the effect on bilirubin metabolism.

Authors:  E Knobloch; I Miler
Journal:  Folia Microbiol (Praha)       Date:  1986       Impact factor: 2.099

3.  Renal handling of bilirubin photoderivatives.

Authors:  M M Elías; E J Comin; J E Ochoa; E A Rodríguez Garay
Journal:  Experientia       Date:  1987-08-15

Review 4.  Use of phototherapy for neonatal hyperbilirubinemia. Fetus and Newborn Committee, Canadian Paediatric Society.

Authors: 
Journal:  CMAJ       Date:  1986-06-01       Impact factor: 8.262

5.  Biliverdin amides reveal roles for propionate side chains in bilin reductase recognition and in holophytochrome assembly and photoconversion.

Authors:  Lixia Shang; Nathan C Rockwell; Shelley S Martin; J Clark Lagarias
Journal:  Biochemistry       Date:  2010-07-27       Impact factor: 3.162

Review 6.  A brief history of phytochromes.

Authors:  Nathan C Rockwell; J Clark Lagarias
Journal:  Chemphyschem       Date:  2010-04-26       Impact factor: 3.102

7.  Wavelength-dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IX alpha bound to human serum albumin. Demonstration of green light at 510 nm as the most effective wavelength in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha via (EZ)-bilirubin.

Authors:  S Onishi; S Itoh; K Isobe
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

8.  Comparison of kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin with that bound to rat serum albumin.

Authors:  S Onishi; S Itoh; T Yamakawa; K Isobe; M Manabe; S Toyota; T Imai
Journal:  Biochem J       Date:  1985-09-15       Impact factor: 3.857

9.  Rapid clearance of a structural isomer of bilirubin during phototherapy.

Authors:  J F Ennever; A T Costarino; R A Polin; W T Speck
Journal:  J Clin Invest       Date:  1987-06       Impact factor: 14.808

10.  A second conserved GAF domain cysteine is required for the blue/green photoreversibility of cyanobacteriochrome Tlr0924 from Thermosynechococcus elongatus.

Authors:  Nathan C Rockwell; Stephanie Lane Njuguna; Laurel Roberts; Elenor Castillo; Victoria L Parson; Sunshine Dwojak; J Clark Lagarias; Susan C Spiller
Journal:  Biochemistry       Date:  2008-06-13       Impact factor: 3.162
  10 in total

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