Literature DB >> 7470068

Demonstration of a geometric isomer of bilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant and the mechanism of jaundice phototherapy.

S Onishi, K Isobe, S Itoh, N Kawade, S Sugiyama.   

Abstract

Photobilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant was demonstrated for the first time by reversed-phase high-pressure liquid chromatography. The concentrations increased significantly during phototherapy. Corresponding to these changes in the serum, biliary unconjugated bilirubin concentrations increased markedly but photobilirubin-IX alpha was not detected in the bile. Moreover, large amounts of 'unknown pigment' that are diazo-negative appeared in the bile during phototherapy.

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Year:  1980        PMID： 7470068      PMCID： PMC1162129          DOI： 10.1042/bj1900533

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

1.  Phototherapy of neonatal jaundice.

Authors:  A F McDonagh
Journal:  Biochem Soc Trans       Date:  1976       Impact factor: 5.407

2.  The structure of bilirubin.

Authors:  R Bonnett; J E Davies; M B Hursthouse; G M Sheldrick
Journal:  Proc R Soc Lond B Biol Sci       Date:  1978-06-23

3.  Structure of bilirubin.

Authors:  R Bonnett; J E Davies; M B Hursthouse
Journal:  Nature       Date:  1976-07-22       Impact factor: 49.962

Review 4.  Recent and changing concepts of hyperbilirubinemia and its management in the newborn.

Authors:  J W Seligman
Journal:  Pediatr Clin North Am       Date:  1977-08       Impact factor: 3.278

5.  Influence of phototherapy on unconjugated bilirubin in duodenal bile of newborn infants with hyperbilirubinemia.

Authors:  H T Lund; J Jacobsen
Journal:  Acta Paediatr Scand       Date:  1972-11

6.  Photobilirubin: an early bilirubin photoproduct detected by absorbance difference spectroscopy.

Authors:  D A Lightner; T A Wooldridge; A F McDonagh
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

7.  High-pressure liquid chromatographic analysis of anaerobic photoproducts of bilirubin-IX alpha in vitro and its comparison with photoproducts in vivo.

Authors:  S Onishi; N Kawade; S Itoh; K Isobe; S Sugiyama
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

8.  Configurational isomerization of bilirubin and the mechanism of jaundice phototherapy.

Authors:  D A Lightner; T A Wooldridge; A F McDonagh
Journal:  Biochem Biophys Res Commun       Date:  1979-01-30       Impact factor: 3.575

9.  Jaundice phototherapy: micro flow-cell photometry reveals rapid biliary response of Gunn rats to light.

Authors:  A F McDonagh; L M Ramonas
Journal:  Science       Date:  1978-09-01       Impact factor: 47.728

10.  Photocatabolism of labeled bilirubin in the congenitally jaundiced (Gunn) rat.

Authors:  J D Ostrow
Journal:  J Clin Invest       Date:  1971-03       Impact factor: 14.808
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  25 in total

1.  Sister Jean Ward, phototherapy, and jaundice: a unique human and photochemical interaction.

Authors:  M J Maisels
Journal:  J Perinatol       Date:  2015-06-11       Impact factor: 2.521

2.  Early formation of bilirubin isomers during phototherapy for neonatal jaundice: effects of single vs. double fluorescent lamps vs. photodiodes.

Authors:  Khalaf Mreihil; Poul Madsen; Britt Nakstad; Jūratė Šaltytė Benth; Finn Ebbesen; Thor Willy Ruud Hansen
Journal:  Pediatr Res       Date:  2015-03-20       Impact factor: 3.756

3.  Effect of the binding of bilirubin to either the first class or the second class of binding sites of the human serum albumin molecule on its photochemical reaction.

Authors:  S Onishi; S Itoh; K Isobe; M Ochi; T Kunikata; T Imai
Journal:  Biochem J       Date:  1989-02-01       Impact factor: 3.857

4.  Current concepts in phototherapy.

Authors:  J F Ennever; V Malhotra
Journal:  Indian J Pediatr       Date:  1986 Sep-Oct       Impact factor: 1.967

5.  Kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin. Demonstration of (EZ)-bilirubin IX alpha as an intermediate in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha.

Authors:  S Itoh; S Onishi
Journal:  Biochem J       Date:  1985-02-15       Impact factor: 3.857

6.  Wavelength-dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IX alpha bound to human serum albumin. Demonstration of green light at 510 nm as the most effective wavelength in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha via (EZ)-bilirubin.

Authors:  S Onishi; S Itoh; K Isobe
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

7.  Comparison of kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin with that bound to rat serum albumin.

Authors:  S Onishi; S Itoh; T Yamakawa; K Isobe; M Manabe; S Toyota; T Imai
Journal:  Biochem J       Date:  1985-09-15       Impact factor: 3.857

8.  Kinetic study of photochemical and thermal conversion of bilirubin IX alpha and its photoproducts.

Authors:  K Isobe; S Itoh; S Onishi; T Yamakawa; T Ogino; T Yokoyama
Journal:  Biochem J       Date:  1983-03-01       Impact factor: 3.857

Review 9.  Neonatal bilirubin toxicity. A review of kernicterus and the implications of drug-induced bilirubin displacement.

Authors:  P C Walker
Journal:  Clin Pharmacokinet       Date:  1987-07       Impact factor: 6.447

10.  Structure and thermal interconversion of cyclobilirubin IX alpha.

Authors:  S Onishi; I Miura; K Isobe; S Itoh; T Ogino; T Yokoyama; T Yamakawa
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857
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