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Literature DB >> 6865947

Procaryotic genomic DNA inhibits mammalian cell transformation.

Abstract

Ltk- mouse cells were transformed to thymidine kinase prototrophy in the presence of carrier DNAs isolated from different organisms. Procaryotic genomic and phage DNA was consistently less effective as a carrier than was eucaryotic DNA. Mixing experiments indicate that DNA of procaryotic origin inhibits mammalian cell transformation.

Entities: Gene Species

Mesh：

Substances：

Year: 1983 PMID： 6865947 PMCID： PMC368618 DOI： 10.1128/mcb.3.5.956-959.1983

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

18 in total

1. Transformation of mammalian cells with genes from procaryotes and eucaryotes.

Authors: M Wigler; R Sweet; G K Sim; B Wold; A Pellicer; E Lacy; T Maniatis; S Silverstein; R Axel
Journal: Cell Date: 1979-04 Impact factor: 41.582

2. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells.

Authors: M Wigler; S Silverstein; L S Lee; A Pellicer; Y c Cheng; R Axel
Journal: Cell Date: 1977-05 Impact factor: 41.582

3. Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus.

Authors: L W Enquist; G F Vande Woude; M Wagner; J R Smiley; W C Summers
Journal: Gene Date: 1979-11 Impact factor: 3.688

4. The transfer and stable integration of the HSV thymidine kinase gene into mouse cells.

Authors: A Pellicer; M Wigler; R Axel; S Silverstein
Journal: Cell Date: 1978-05 Impact factor: 41.582

5. Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor.

Authors: M Wigler; A Pellicer; S Silverstein; R Axel
Journal: Cell Date: 1978-07 Impact factor: 41.582

6. Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli.

Authors: D B Clewell; D R Helinski
Journal: J Bacteriol Date: 1972-06 Impact factor: 3.490

7. A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors: F L Graham; A J van der Eb
Journal: Virology Date: 1973-04 Impact factor: 3.616

8. Intraspecies transfer via total cellular DNA of the gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells.

Authors: K Willecke; M Klomfass; R Mierau; J Döhmer
Journal: Mol Gen Genet Date: 1979-02-26

Procaryotic genomic DNA inhibits mammalian cell transformation.

1. Transformation of mammalian cells with genes from procaryotes and eucaryotes.

2. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells.

3. Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus.

4. The transfer and stable integration of the HSV thymidine kinase gene into mouse cells.

5. Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor.

6. Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli.

7. A new technique for the assay of infectivity of human adenovirus 5 DNA.

8. Intraspecies transfer via total cellular DNA of the gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells.

9. Isolation of the chicken thymidine kinase gene by plasmid rescue.

10. DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1. Efficient transfer of cloned DNA into human diploid cells: protoplast fusion in suspension.

2. Molecular cloning of the mouse ouabain-resistance gene.

3. Integration and expression of several molecular forms of Rous sarcoma virus DNA used for transfection of mouse cells.

4. Enhanced transformation of human cells by UV-irradiated pSV2 plasmids.