| Literature DB >> 6647028 |
C Schattenkerk, G M Visser, G A van der Marel, J H van Boom.
Abstract
The bifunctional and crystalline phosphorylating agent morpholino-0,0-bis[1-benzotriazolyl]phosphate has been used for the preparation of a 3',5'-bis-phosphotriester intermediate of thymidine. The latter has been converted into ppTppp by the following consecutive steps; removal of the benzotriazolyl group followed by the addition of phosphoric acid and removal of the 2-(4-nitrophenyl)-ethyl group followed by the addition of pyrophosphoric acid.Entities:
Mesh：
Substances：
Year: 1983 PMID： 6647028 PMCID： PMC326501 DOI： 10.1093/nar/11.21.7545
Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971