| Literature DB >> 6631963 |
G A Bentley, M Delepierre, C M Dobson, R E Wedin, S A Mason, F M Poulsen.
Abstract
A preliminary comparison of the solvent exchange of individual hydrogens of a protein in solution and in a crystal has been possible by using data for lysozyme from 1H nuclear magnetic resonance and neutron diffraction studies. It is suggested that this approach enables a direct comparison of local dynamical behaviour in the two states. The results indicate markedly similar behaviour for many residues, but significant differences are indicated in several regions of the protein.Entities:
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Year: 1983 PMID： 6631963 DOI： 10.1016/s0022-2836(83)80235-6
Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469