Literature DB >> 6586634

Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen----q131) and adenosine deaminase (q131----qter) on chromosome 20.

T Mohandas, R S Sparkes, E J Suh, M S Hershfield.   

Abstract

The gene loci for S-adenosylhomocysteine hydrolase ( AHCY ) and adenosine deaminase (ADA), two enzymes with related metabolic functions, have both been assigned to human chromosome 20. We have used rodent-human somatic hybrids containing translocations involving human chromosome 20 to more precisely determine the relative locations of the AHCY and ADA loci. Our results assign the AHCY locus to the long arm of chromosome 20, in the region cen---- q131 , and ADA to the region q131 ----qter.

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Year:  1984        PMID： 6586634     DOI： 10.1007/bf00287630

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  20 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  Genetics of human cess line. IV. DNA-mediated heritable transformation of a biochemical trait.

Authors:  E H SZYBALSKA; W SZYBALSKI
Journal:  Proc Natl Acad Sci U S A       Date:  1962-12-15       Impact factor: 11.205

3.  Ouabain as a selective agent in the isolation of somatic cell hybrids.

Authors:  R S Kucherlapati; R M Baker; F H Ruddle
Journal:  Cytogenet Cell Genet       Date:  1975

Review 4.  Report of the committee on the genetic constitution of chromosomes 13, 14, 15, 16, 17, 18, 19, 20, 21, and 22.

Authors:  M A Ferguson-Smith; A Westerveld
Journal:  Cytogenet Cell Genet       Date:  1979

5.  Assignment of a gene for adenosine deaminase to human chromosome 20.

Authors:  J A Tischfield; R P Creagan; E A Nichols; F H Ruddle
Journal:  Hum Hered       Date:  1974       Impact factor: 0.444

6.  Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.

Authors:  M S Hershfield
Journal:  J Biol Chem       Date:  1979-01-10       Impact factor: 5.157

7.  S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.

Authors:  N M Kredich; M S Hershfield
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

8.  Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol.

Authors:  R L Davidson; P S Gerald
Journal:  Somatic Cell Genet       Date:  1976-03

9.  Genetics of human S-adenosylhomocysteine hydrolase. A new polymorphism in man.

Authors:  S Bissbort; K Bender; T F Wienker; K H Grzeschik
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

10.  The human genes for S-adenosylhomocysteine hydrolase and adenosine deaminase are syntenic on chromosome 20.

Authors:  M S Hershfield; U Francke
Journal:  Science       Date:  1982-05-14       Impact factor: 47.728
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  19 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Four distinct alpha satellite subfamilies shared by human chromosomes 13, 14 and 21.

Authors:  B Vissel; K H Choo
Journal:  Nucleic Acids Res       Date:  1991-01-25       Impact factor: 16.971

3.  Assignment of the human and mouse prion protein genes to homologous chromosomes.

Authors:  R S Sparkes; M Simon; V H Cohn; R E Fournier; J Lem; I Klisak; C Heinzmann; C Blatt; M Lucero; T Mohandas
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

Review 4.  Mouse chromosome 2.

Authors:  L D Siracusa; C M Abbott
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Identification and characterization of nine RFLPs at the adenosine deaminase (ADA) locus.

Authors:  S Tzall; A Ellenbogen; F Eng; R Hirschhorn
Journal:  Am J Hum Genet       Date:  1989-06       Impact factor: 11.025

Review 7.  The map of chromosome 20.

Authors:  N E Simpson
Journal:  J Med Genet       Date:  1988-12       Impact factor: 6.318

8.  Expression of human adenosine deaminase in murine hematopoietic cells.

Authors:  J W Belmont; G R MacGregor; K Wager-Smith; F A Fletcher; K A Moore; D Hawkins; D Villalon; S M Chang; C T Caskey
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272

9.  Assignment of a human beta-crystallin gene to 17cen-q23.

Authors:  R S Sparkes; T Mohandas; C Heinzmann; M B Gorin; S Zollman; J Horwitz
Journal:  Hum Genet       Date:  1986-10       Impact factor: 4.132

10.  S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization.

Authors:  M S Hershfield; V N Aiyar; R Premakumar; W C Small
Journal:  Biochem J       Date:  1985-08-15       Impact factor: 3.857
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