Literature DB >> 6514575

Filter disc supported oligonucleotide synthesis by the phosphite method.

J Ott, F Eckstein.   

Abstract

The phosphite approach to oligodeoxynucleotide synthesis has been applied to the filter disc support. The method is exemplified here by the preparation of eight decadeoxynucleotides.

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Year:  1984        PMID： 6514575      PMCID： PMC320443          DOI： 10.1093/nar/12.23.9137

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  8 in total

1.  Methylphosphonates as probes of protein-nucleic acid interactions.

Authors:  S A Noble; E F Fisher; M H Caruthers
Journal:  Nucleic Acids Res       Date:  1984-04-11       Impact factor: 16.971

Review 2.  Synthesis and use of synthetic oligonucleotides.

Authors:  K Itakura; J J Rossi; R B Wallace
Journal:  Annu Rev Biochem       Date:  1984       Impact factor: 23.643

3.  Improvements in the phosphoramidite procedure for the synthesis of oligodeoxyribonucleotides.

Authors:  T Dörper; E L Winnacker
Journal:  Nucleic Acids Res       Date:  1983-05-11       Impact factor: 16.971

4.  New effective method for the synthesis of oligonucleotides via phosphotriester intermediates.

Authors:  V A Efimov; S V Reverdatto; O G Chakhmakhcheva
Journal:  Nucleic Acids Res       Date:  1982-11-11       Impact factor: 16.971

5.  Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site.

Authors:  B A Connolly; B V Potter; F Eckstein; A Pingoud; L Grotjahn
Journal:  Biochemistry       Date:  1984-07-17       Impact factor: 3.162

6.  Rapid synthesis of oligodeoxyribonucleotides. VII. Solid phase synthesis of oligodeoxyribonucleotides by a continuous flow phosphotriester method on a kieselguhr-polyamide support.

Authors:  M J Gait; H W Matthes; M Singh; B S Sproat; R C Titmas
Journal:  Nucleic Acids Res       Date:  1982-10-25       Impact factor: 16.971

7.  A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports.

Authors:  R Frank; W Heikens; G Heisterberg-Moutsis; H Blöcker
Journal:  Nucleic Acids Res       Date:  1983-07-11       Impact factor: 16.971

8.  Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale.

Authors:  H W Matthes; W M Zenke; T Grundström; A Staub; M Wintzerith; P Chambon
Journal:  EMBO J       Date:  1984-04       Impact factor: 11.598
  8 in total
  7 in total

1.  The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA.

Authors:  J W Taylor; J Ott; F Eckstein
Journal:  Nucleic Acids Res       Date:  1985-12-20       Impact factor: 16.971

2.  The influence of exocyclic substituents of purine bases on DNA curvature.

Authors:  S Diekmann; E von Kitzing; L McLaughlin; J Ott; F Eckstein
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

Review 3.  Site-directed mutagenesis.

Authors:  P Carter
Journal:  Biochem J       Date:  1986-07-01       Impact factor: 3.857

4.  Temperature and salt dependence of the gel migration anomaly of curved DNA fragments.

Authors:  S Diekmann
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

5.  Mechanistic studies on the phosphoramidite coupling reaction in oligonucleotide synthesis. I. Evidence for nucleophilic catalysis by tetrazole and rate variations with the phosphorus substituents.

Authors:  B H Dahl; J Nielsen; O Dahl
Journal:  Nucleic Acids Res       Date:  1987-02-25       Impact factor: 16.971

6.  Analytical studies of 'mixed sequence' oligodeoxyribonucleotides synthesized by competitive coupling of either methyl- or beta-cyanoethyl-N,N-diisopropylamino phosphoramidite reagents, including 2'-deoxyinosine.

Authors:  G Zon; K A Gallo; C J Samson; K L Shao; M F Summers; R A Byrd
Journal:  Nucleic Acids Res       Date:  1985-11-25       Impact factor: 16.971

7.  DNA methylation can enhance or induce DNA curvature.

Authors:  S Diekmann
Journal:  EMBO J       Date:  1987-12-20       Impact factor: 11.598
  7 in total

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