Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Human chromosome hot points. 1. Hot point at 3p14 in three populations.

Literature DB >> 6469239

Human chromosome hot points. 1. Hot point at 3p14 in three populations.

X T Zhou, B H Xu, C L Chu, G F Xia, N Li, R Sha.

Abstract

A chromosome hot point, 3p14, in healthy peasants, mentally retarded patients (MR), and epileptic patients (EP) was studied. The frequency of the hot point, 3p14 break, was significantly higher in EP. It may be caused by folic acid reduction in patients' serum induced by the antiepileptic drugs. The difference between hot point and fragile site is discussed.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Anticonvulsants

Year: 1984 PMID： 6469239 DOI： 10.1007/bf00291350

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

11 in total

1. Folic acid and neuropathy in epilepsy.

Authors: D G Wells
Journal: Lancet Date: 1968-01-20 Impact factor: 79.321

2. Folic acid and anticonvulsants.

Authors: N M Viukari
Journal: Lancet Date: 1968-05-04 Impact factor: 79.321

3. Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patients.

Authors: E H Reynolds; R H Mattson; B B Gallagher
Journal: Neurology Date: 1972-08 Impact factor: 9.910

4. Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.

Authors: E H Reynolds; I Chanarin; G Milner; D M Matthews
Journal: Epilepsia Date: 1966-12 Impact factor: 5.864

5. Chromosome abnormalities in lymphocytes from normal human subjects. A study of 3,720 cells.

Authors: H A Lubs; J Samuelson
Journal: Cytogenetics Date: 1967

6. A new familial "fragile site" on chromosome 16 (q23-24). Cytogenetic and clinical considerations.

Authors: F Shabtai; D Klar; R Nissimov; D Vardimon; J Hart; I Halbrecht
Journal: Hum Genet Date: 1983 Impact factor: 4.132

7. A new heritable fragile site on human chromosome 3.

Authors: C Rudduck; G Franzén
Journal: Hereditas Date: 1983 Impact factor: 3.271

8. Methotrexate-induced increase in gap formation in human chromosome band 3p14.

Authors: A Markkanen; K Heinonen; S Knuutila; A de la Chapelle
Journal: Hereditas Date: 1982 Impact factor: 3.271

9. 5-Fluoro-2'-deoxyuridine induction of the fragile site on Xq28 associated with X linked mental retardation.

Authors: N Tommerup; H Poulsen; K Brøndum-Nielsen
Journal: J Med Genet Date: 1981-10 Impact factor: 6.318

10. A new inducible fragile site on chromosome 3(p14.2) in human lymphocytes.

Authors: R D Wegner
Journal: Hum Genet Date: 1983 Impact factor: 4.132

9 in total

1. Medical genetics in China.

Authors: L Hui-Yuan
Journal: J Med Genet Date: 1988-04 Impact factor: 6.318

2. Fragile sites induced by FUdR, caffeine, and aphidicolin. Their frequency, distribution, and analysis.

Authors: P N Rao; N A Heerema; C G Palmer
Journal: Hum Genet Date: 1988-01 Impact factor: 4.132

3. Rare, polymorphic, and common fragile sites: a classification.

Authors: F Hecht
Journal: Hum Genet Date: 1986-10 Impact factor: 4.132

4. The effect of 1-beta-D-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14.

Authors: X Z Li; Z A Yan; X T Zhou
Journal: Hum Genet Date: 1986-12 Impact factor: 4.132

5. The effect of hydroxyurea on the expression of the common fragile site at 3p14.

Authors: Z A Yan; X Z Li; X T Zhou
Journal: J Med Genet Date: 1987-10 Impact factor: 6.318

6. Expression of folate-sensitive fragile sites in lymphocyte chromosomes.

Authors: C Fuster; R Miró; C Templado; L Barrios; J Egozcue
Journal: Hum Genet Date: 1989-02 Impact factor: 4.132

7. The most common fragile site in man is 3p14.

Authors: D F Smeets; J M Scheres; T W Hustinx
Journal: Hum Genet Date: 1986-03 Impact factor: 4.132

8. Human chromosome hot points. V. The effect of four nucleosides on chromosomes in folate-free medium.

Authors: N Li; Y Wu; X T Zhou
Journal: Hum Genet Date: 1986-09 Impact factor: 4.132

9. Human chromosome hot points. IV. Uridine-induced hot-point breaks at 3p14 and 16q23-24 and increased expression of fragile site Xq27 in folate-free medium.

Authors: N Li; X T Zhou
Journal: Hum Genet Date: 1985 Impact factor: 4.132

9 in total