| Literature DB >> 6310526 |
A Tsimanis, V Bichko, D Dreilina, J Meldrais, V Lozha, R Kukaine, E Gren.
Abstract
cDNA synthesized on the bovine leukemia virus RNA template has been cloned in the pBR322 Pst I site. Colony hybridization with BLV RNA fragments and oligo (dT) has revealed a clone with cDNA insert containing 660 3'-terminal nucleotides of the BLV genome. The nucleotide sequence of the insert corresponding to U3 and R regions of the long terminal repeats (LTR) of viral genome has been determined. BLV U3, like U3 of other retroviruses, presumably contains promoter. The unusually long R region (about 230 bp), a certain homology with ATLV U3-R and some other structural features allow to group BLV LTR together with ATLV LTR in a separate class of retroviral LTR.Entities:
Mesh:
Substances:
Year: 1983 PMID: 6310526 PMCID: PMC326336 DOI: 10.1093/nar/11.17.6079
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971