Literature DB >> 6309587

DNA insertion sequences near the insulin gene are not associated with maturity-onset diabetes of young people.

D Owerbach, B Thomsen, K Johansen, L U Lamm, J Nerup.   

Abstract

The association between DNA insertion sequences located near the insulin gene and the dominantly inherited maturity-onset diabetes of young people was studied in a large family. The distribution of the restriction fragments was compatible with Mendelian segregation. However, no linkage was found between the DNA insertion sequences and this form of diabetes.

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Year:  1983        PMID： 6309587     DOI： 10.1007/bf00251890

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  13 in total

1.  The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.

Authors:  N E MORTON
Journal:  Am J Hum Genet       Date:  1956-06       Impact factor: 11.025

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Assignment of the major histocompatibility complex to chromosome No. 6 in a family with a pericentric inversion.

Authors:  L U Lamm; U Friedrich; C B Petersen; J Jorgensen; J Nielsen; A J Therkelsen; F Kissmeyer-Nielsen
Journal:  Hum Hered       Date:  1974       Impact factor: 0.444

4.  DNA insertion sequences near the insulin gene affect glucose regulation.

Authors:  D Owerbach; S Poulsen; P Billesbølle; J Nerup
Journal:  Lancet       Date:  1982-04-17       Impact factor: 79.321

5.  Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

Authors:  G I Bell; J H Karam; W J Rutter
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

6.  Polymorphism in the 5'-flanking region of the human insulin gene and its possible relation to type 2 diabetes.

Authors:  P Rotwein; R Chyn; J Chirgwin; B Cordell; H M Goodman; M A Permut
Journal:  Science       Date:  1981-09-04       Impact factor: 47.728

7.  No evidence for linkage between HLA and maturity onset type of diabetes in young people.

Authors:  P Platz; B K Jakobsen; A Svejgaard; B S Thomsen; K B Jensen; K Henningsen; L U Lamm
Journal:  Diabetologia       Date:  1982-07       Impact factor: 10.122

8.  Possible association between DNA sequences flanking the insulin gene and atherosclerosis.

Authors:  D Owerbach; K Johansen; P Billesbølle; S Poulsen; M Schroll; J Nerup
Journal:  Lancet       Date:  1982-12-11       Impact factor: 79.321

9.  Polymorphism in the 5' flanking region of the human insulin gene: a genetic marker for non-insulin-dependent diabetes.

Authors:  P S Rotwein; J Chirgwin; M Province; W C Knowler; D J Pettitt; B Cordell; H M Goodman; M A Permutt
Journal:  N Engl J Med       Date:  1983-01-13       Impact factor: 91.245

10.  Restriction fragment length polymorphism of the insulin gene in diabetes mellitus.

Authors:  D Owerbach; J Nerup
Journal:  Diabetes       Date:  1982-03       Impact factor: 9.461
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  7 in total

1.  Multipoint linkage analysis of the short arm of chromosome 11 in non-insulin dependent diabetes including maturity onset diabetes of youth.

Authors:  S O'Rahilly; P Patel; O J Lehmann; A Tybjaerg-Hansen; J Nerup; R C Turner; J S Wainscoat
Journal:  Hum Genet       Date:  1992-05       Impact factor: 4.132

2.  Linkage analysis of the human insulin receptor gene and maturity onset diabetes of the young.

Authors:  S C Elbein; I Borecki; L Corsetti; S S Fajans; A T Hansen; J Nerup; M Province; M A Permutt
Journal:  Diabetologia       Date:  1987-08       Impact factor: 10.122

3.  The genetic predisposition to fibrocalculous pancreatic diabetes.

Authors:  P K Kambo; G A Hitman; V Mohan; A Ramachandran; C Snehalatha; S Suresh; K Metcalfe; B K Ryait; M Viswanathan
Journal:  Diabetologia       Date:  1989-01       Impact factor: 10.122

Review 4.  Insulin-gene flanking sequences, diabetes mellitus and atherosclerosis: a review.

Authors:  T Mandrup-Poulsen; D Owerbach; J Nerup; K Johansen; J Ingerslev; A T Hansen
Journal:  Diabetologia       Date:  1985-08       Impact factor: 10.122

5.  Diabetes mellitus, atherosclerosis, and the 5' flanking polymorphism of the human insulin gene.

Authors:  T Mandrup-Poulsen; D Owerbach; J Nerup; K Johansen; A Tybjaerg Hansen
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

6.  Polymorphism in the 5' flanking region of the human insulin gene. Relationships with noninsulin-dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians.

Authors:  W C Knowler; D J Pettitt; B Vasquez; P S Rotwein; T L Andreone; M A Permutt
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808

7.  Possible correlation between non-insulin dependent diabetes mellitus (NIDDM) and restriction fragment length polymorphism (RFLP) of the 5'-flanking region of insulin gene in Korean diabetic population.

Authors:  S W Kim; I M Yang; J W Kim; Y S Kim; Y K Choi
Journal:  Korean J Intern Med       Date:  1987-07       Impact factor: 2.884
  7 in total

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