Literature DB >> 6306772

Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus.

M Mercola, X F Wang, J Olsen, K Calame.   

Abstract

Two regions in the immunoglobulin heavy chain locus were tested for their ability to enhance transcription of the SV40 early promoter. A portion of the intervening sequence between the heavy chain joining region (Jh) and the constant region of the mu chain (Cmu) can enhance transcription when it is cloned either 5' or 3' to the SV40 early promoter. The region between C alpha and the alpha switch site, which occurs 5' to the translocated c-myc oncogene in many murine plasmacytomas, does not show transcriptional enhancer activity in this assay.

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Year:  1983        PMID： 6306772     DOI： 10.1126/science.6306772

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  55 in total

1.  A highly conserved intronic sequence is involved in transcriptional regulation of the alpha 1(I) collagen gene.

Authors:  D J Liska; J L Slack; P Bornstein
Journal:  Cell Regul       Date:  1990-05

Review 2.  Towards a comprehensive catalogue of validated and target-linked human enhancers.

Authors:  Molly Gasperini; Jacob M Tome; Jay Shendure
Journal:  Nat Rev Genet       Date:  2020-01-27       Impact factor: 53.242

3.  Identification of a T-cell-specific transcriptional enhancer located 3' of C gamma 1 in the murine T-cell receptor gamma locus.

Authors:  D M Spencer; Y H Hsiang; J P Goldman; D H Raulet
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

4.  In vitro transcription of immunoglobulin genes in a B-cell extract: effects of enhancer and promoter sequences.

Authors:  R Sen; D Baltimore
Journal:  Mol Cell Biol       Date:  1987-05       Impact factor: 4.272

5.  Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer.

Authors:  J L Imler; C Lemaire; C Wasylyk; B Wasylyk
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

Review 6.  Regulation of disease-associated gene expression in the 3D genome.

Authors:  Peter Hugo Lodewijk Krijger; Wouter de Laat
Journal:  Nat Rev Mol Cell Biol       Date:  2016-11-09       Impact factor: 94.444

7.  Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA.

Authors:  C L Peterson; K Orth; K L Calame
Journal:  Mol Cell Biol       Date:  1986-12       Impact factor: 4.272

8.  An active chromatin structure acquired by translocated c-myc genes.

Authors:  E Kakkis; J Prehn; K Calame
Journal:  Mol Cell Biol       Date:  1986-04       Impact factor: 4.272

9.  Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

Authors:  H Potter; L Weir; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

10.  An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite.

Authors:  R Hen; E Borrelli; P Sassone-Corsi; P Chambon
Journal:  Nucleic Acids Res       Date:  1983-12-20       Impact factor: 16.971
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