Literature DB >> 6292855

Multiple arrangements of the human embryonic zeta globin genes.

P Winichagoon, D R Higgs, S E Goodbourn, J Lamb, J B Clegg, D J Weatherall.   

Abstract

Rearrangements which are most readily explained by homologous crossover between misaligned segments of DNA in the region of the human embryonic zeta (zeta) globin genes have been identified in individuals of three different racial origins. These recombination events have resulted in a surprisingly high prevalence of chromosomes with single (0.4%) and triplicated (1.3%) zeta genes with apparently no significant effect on the phenotype.

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Year:  1982        PMID： 6292855      PMCID： PMC320935          DOI： 10.1093/nar/10.19.5853

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  23 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

Authors:  S H Embury; R V Lebo; A M Dozy; Y W Kan
Journal:  J Clin Invest       Date:  1979-06       Impact factor: 14.808

3.  Hemoglobin Kenya, the product of fusion of amd polypeptide chains.

Authors:  T H Huisman; R N Wrightstone; J B Wilson; W A Schroeder; A G Kendall
Journal:  Arch Biochem Biophys       Date:  1972-12       Impact factor: 4.013

4.  Molecular cloning and characterization of the human beta-like globin gene cluster.

Authors:  E F Fritsch; R M Lawn; T Maniatis
Journal:  Cell       Date:  1980-04       Impact factor: 41.582

5.  Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay.

Authors:  A Deisseroth; A Nienhuis; P Turner; R Velez; W F Anderson; F Ruddle; J Lawrence; R Creagan; R Kucherlapati
Journal:  Cell       Date:  1977-09       Impact factor: 41.582

6.  Organization of human delta--and beta-globin genes in cellular DNA and the presence of intragenic inserts.

Authors:  J G Mears; F Ramirez; D Leibowitz; A Bank
Journal:  Cell       Date:  1978-09       Impact factor: 41.582

7.  Triplicated alpha-globin loci in humans.

Authors:  M Goossens; A M Dozy; S H Embury; Z Zachariades; M G Hadjiminas; G Stamatoyannopoulos; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

8.  Rapid duplication and loss of genes coding for the alpha chains of hemoglobin.

Authors:  E A Zimmer; S L Martin; S M Beverley; Y W Kan; A C Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

9.  The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease.

Authors:  S H Orkin; J Old; H Lazarus; C Altay; A Gurgey; D J Weatherall; D G Nathan
Journal:  Cell       Date:  1979-05       Impact factor: 41.582

10.  A novel alpha-globin gene arrangement in man.

Authors:  D R Higgs; J M Old; L Pressley; J B Clegg; D J Weatherall
Journal:  Nature       Date:  1980-04-17       Impact factor: 49.962
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  19 in total

1.  Globin genes in Micronesia: origins and affinities of Pacific Island peoples.

Authors:  D F O'Shaughnessy; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

2.  Melanesians and Polynesians share a unique alpha-thalassemia mutation.

Authors:  A V Hill; D K Bowden; R J Trent; D R Higgs; S J Oppenheimer; S L Thein; K N Mickleson; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1985-05       Impact factor: 11.025

3.  Different zeta globin gene deletions among black Americans.

Authors:  A E Felice; M P Cleek; E M Marino; K M McKie; V C McKie; B K Chang; T H Huisman
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132

4.  Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.

Authors:  D R Higgs; J S Wainscoat; J Flint; A V Hill; S L Thein; R D Nicholls; H Teal; H Ayyub; T E Peto; A G Falusi
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

5.  An elongated segment of DNA observed between two human alpha globin genes.

Authors:  T Nakatsuji; H Landman; T H Huisman
Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

6.  Different hematologic phenotypes are associated with the leftward (-alpha 4.2) and rightward (-alpha 3.7) alpha+-thalassemia deletions.

Authors:  D K Bowden; A V Hill; D R Higgs; S J Oppenheimer; D J Weatherall; J B Clegg
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

7.  Globin genes in Polynesians have many rearrangements including a recently described gamma gamma gamma gamma/.

Authors:  R J Trent; K N Mickleson; T Wilkinson; J Yakas; M W Dixon; P J Hill; H Kronenberg
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

Review 8.  The evolution of the alpha- and beta-globin gene clusters in human populations.

Authors:  A V Hill; J S Wainscoat
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132

9.  A large deletion encompassing the entire alpha-like globin gene cluster in a family of northern European extraction.

Authors:  P Fortina; K Delgrosso; E Rappaport; M Poncz; S K Ballas; E Schwartz; S Surrey
Journal:  Nucleic Acids Res       Date:  1988-12-09       Impact factor: 16.971

10.  Alpha-globin gene cluster haplotypes in the Kalahari San and southern African Bantu-speaking blacks.

Authors:  M Ramsay; T Jenkins
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025
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