Literature DB >> 6273791

The endogenous proviral mouse mammary tumor virus genes of the GR mouse are not identical and only one corresponds to the exogenous virus.

P Herrlich, N E Hynes, H Ponta, U Rahmsdorf, N Kennedy, B Groner.   

Abstract

The endogenous proviral copies of mouse mammary tumor virus (MMTV) were selected from a gene library of GR mouse DNA. We obtained five different lambda. MMTV recombinant clones. Four of them correspond to the 3' Eco RI fragments of the endogenous proviruses an one comprises an intact MMTV provirus with 2 to 3 kb of flanking mouse genomic DNA. Heteroduplex formation followed by S1 digestion under stringent conditions shows that there is nucleotide sequence heterology among the cloned endogenous proviral copies. Only one endogenous proviral copy, associated with the mtv-2 locus, was found to be totally homologous to the exogenous proviral DNA.

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Year:  1981        PMID: 6273791      PMCID: PMC327493          DOI: 10.1093/nar/9.19.4981

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  17 in total

1.  Genetic control of endogenous murine mammary tumour viruses reinvestigated.

Authors:  P Bentvelzen; J Brinkhof; J J Haaijman
Journal:  Eur J Cancer       Date:  1978-10       Impact factor: 9.162

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Differences between genomes of two strains of mouse mammary tumor virus as shown by partial RNA sequence analysis.

Authors:  R Friedrich; V L Morris; H M Goodman; J M Bishop; H E Varmus
Journal:  Virology       Date:  1976-07-15       Impact factor: 3.616

4.  Packaging recombinant DNA molecules into bacteriophage particles in vitro.

Authors:  B Hohn; K Murray
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

5.  Note on a new inbred mouse-strain GR-A.

Authors:  O Mühlbock
Journal:  Eur J Cancer       Date:  1965-10       Impact factor: 9.162

6.  Integration of the DNA of mouse mammary tumor virus in virus-infected normal and neoplastic tissue of the mouse.

Authors:  J C Cohen; P R Shank; V L Morris; R Cardiff; H E Varmus
Journal:  Cell       Date:  1979-02       Impact factor: 41.582

7.  Organization of mouse mammary tumor virus-specific DNA endogenous to BALB/c mice.

Authors:  J C Cohen; J E Majors; H E Varmus
Journal:  J Virol       Date:  1979-11       Impact factor: 5.103

8.  Endogenous mammary tumour virus DNA varies among wild mice and segregates during inbreeding.

Authors:  J C Cohen; H E Varmus
Journal:  Nature       Date:  1979-03-29       Impact factor: 49.962

9.  Number and location of mouse mammary tumor virus proviral DNA in mouse DNA of normal tissue and of mammary tumors.

Authors:  B Groner; N E Hynes
Journal:  J Virol       Date:  1980-03       Impact factor: 5.103

10.  Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells.

Authors:  N E Hynes; N Kennedy; U Rahmsdorf; B Groner
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205

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  6 in total

1.  Characterization of an endogenous retrovirus-repetitive DNA chimera in the mouse genome.

Authors:  T G Fanning; D W Morris; R D Cardiff; H D Bradshaw
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

2.  Vitellogenin genes A1 and B1 are linked in the Xenopus laevis genome.

Authors:  W Wahli; J E Germond; B ten Heggeler; F E May
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

3.  Isolation and characterisation of the Xenopus laevis albumin genes: loss of 74K albumin gene sequences by library amplification.

Authors:  F E May; R Weber; B R Westley
Journal:  Nucleic Acids Res       Date:  1982-05-11       Impact factor: 16.971

4.  Comparison of the whey acidic protein genes of the rat and mouse.

Authors:  S M Campbell; J M Rosen; L G Hennighausen; U Strech-Jurk; A E Sippel
Journal:  Nucleic Acids Res       Date:  1984-11-26       Impact factor: 16.971

5.  The chromosomal integration site determines the tissue-specific methylation of mouse mammary tumour virus proviral genes.

Authors:  W H Günzburg; B Groner
Journal:  EMBO J       Date:  1984-05       Impact factor: 11.598

6.  Glucocorticoid receptors recognize DNA sequences in and around murine mammary tumour virus DNA.

Authors:  S Geisse; C Scheidereit; H M Westphal; N E Hynes; B Groner; M Beato
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

  6 in total

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