Literature DB >> 6272213

Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.

J C Boothroyd, C A Paynter, G A Cross, A Bernards, P Borst.   

Abstract

cDNAs coding for the amino and carboxy termini of two trypanosome variant surface glycoproteins (VSGs) have been sequenced. The results indicate that VSGs are synthesised with hydrophobic amino-terminal leader and carboxy-terminal tail sequences which are absent from purified mature VSGs.

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Year:  1981        PMID： 6272213      PMCID： PMC327471          DOI： 10.1093/nar/9.18.4735

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  18 in total

1.  Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei.

Authors:  G A Cross
Journal:  Parasitology       Date:  1975-12       Impact factor: 3.234

2.  N-terminal amino acid sequences of variant-specific surface antigens from Trypanosoma brucei.

Authors:  P J Bridgen; G A Cross; J Bridgen
Journal:  Nature       Date:  1976-10-14       Impact factor: 49.962

Review 3.  Antigenic variation in trypanosomes.

Authors:  G A Cross
Journal:  Proc R Soc Lond B Biol Sci       Date:  1978-06-05

4.  Selective cleavage of variant surface glycoproteins from Trypanosoma brucei.

Authors:  J G Johnson; G A Cross
Journal:  Biochem J       Date:  1979-03-15       Impact factor: 3.857

5.  Further procedures for sequence analysis by computer.

Authors:  R Staden
Journal:  Nucleic Acids Res       Date:  1978-03       Impact factor: 16.971

6.  The ovalbumin gene-sequence of putative control regions.

Authors:  C Benoist; K O'Hare; R Breathnach; P Chambon
Journal:  Nucleic Acids Res       Date:  1980-01-11       Impact factor: 16.971

7.  The mechanism of protein secretion across membranes.

Authors:  B D Davis; P C Tai
Journal:  Nature       Date:  1980-01-31       Impact factor: 49.962

8.  Glycopeptides from variant surface glycoproteins of Trypanosoma Brucei. C-terminal location of antigenically cross-reacting carbohydrate moieties.

Authors:  A A Holder; G A Cross
Journal:  Mol Biochem Parasitol       Date:  1981-02       Impact factor: 1.759

9.  Antigenic variation in trypanosomes.

Authors:  K Vickerman
Journal:  Nature       Date:  1978-06-22       Impact factor: 49.962

10.  Novel expression-linked copies of the genes for variant surface antigens in trypanosomes.

Authors:  J H Hoeijmakers; A C Frasch; A Bernards; P Borst; G A Cross
Journal:  Nature       Date:  1980-03-06       Impact factor: 49.962
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  28 in total

1.  Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion.

Authors:  J D Bangs; D M Ransom; M A McDowell; E M Brouch
Journal:  EMBO J       Date:  1997-07-16       Impact factor: 11.598

Review 2.  Molecular biology of trypanosome antigenic variation.

Authors:  J E Donelson; A C Rice-Ficht
Journal:  Microbiol Rev       Date:  1985-06

3.  Duplication and transcription of procyclin genes in Trypanosoma brucei.

Authors:  E König; H Delius; M Carrington; R O Williams; I Roditi
Journal:  Nucleic Acids Res       Date:  1989-11-11       Impact factor: 16.971

4.  Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein.

Authors:  J D Bangs; D Hereld; J L Krakow; G W Hart; P T Englund
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

5.  Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase.

Authors:  M J Weiss; P S Henthorn; M A Lafferty; C Slaughter; M Raducha; H Harris
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

6.  Glycosyl-phosphatidylinositol anchor attachment in a yeast in vitro system.

Authors:  T L Doering; R Schekman
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

7.  Reverse transcription of trypanosome variable antigen mRNAs initiated by a specific oligonucleotide primer.

Authors:  S C Merritt; C Tschudi; W H Konigsberg; F F Richards
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

8.  Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei.

Authors:  H K Majumder; J C Boothroyd; H Weber
Journal:  Nucleic Acids Res       Date:  1981-09-25       Impact factor: 16.971

9.  Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei.

Authors:  L H Van der Ploeg; A Bernards; F A Rijsewijk; P Borst
Journal:  Nucleic Acids Res       Date:  1982-01-22       Impact factor: 16.971

10.  Glycosylphosphatidylinositol-dependent secretory transport in Trypanosoma brucei.

Authors:  M A McDowell; D M Ransom; J D Bangs
Journal:  Biochem J       Date:  1998-11-01       Impact factor: 3.857
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