Literature DB >> 6170939

Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei.

H K Majumder, J C Boothroyd, H Weber.   

Abstract

Sequences corresponding to the complete 3'-terminal regions of the messenger RNAs for three different Variant Surface Glycoproteins of Trypanosoma brucei were determined on complementary DNA inserts cloned in recombinant plasmids. The three sequences show 80-130 base pair long segments of strong (70-80%) homology at the 3' ends, whereas ther regions upstream from the last 130-140 base pairs contain no significant homology. The signal AAUAAA, present near the 3' ends of almost all known polyadenylated mRNAs of eukaryotes, does not occur in the 3'-terminal sequences of these three variants.

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Year:  1981        PMID： 6170939      PMCID： PMC327472          DOI： 10.1093/nar/9.18.4745

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  15 in total

Review 1.  Glycoproteins.

Authors:  R D Marshall
Journal:  Annu Rev Biochem       Date:  1972       Impact factor: 23.643

2.  Genomic rearrangements correlated with antigenic variation in Trypanosoma brucei.

Authors:  R O Williams; J R Young; P A Majiwa
Journal:  Nature       Date:  1979 Dec 20-27       Impact factor: 49.962

3.  3' non-coding region sequences in eukaryotic messenger RNA.

Authors:  N J Proudfoot; G G Brownlee
Journal:  Nature       Date:  1976-09-16       Impact factor: 49.962

4.  Crossreacting determinants in the C-terminal region of trypanosome variant surface antigens.

Authors:  G A Cross
Journal:  Nature       Date:  1979-01-25       Impact factor: 49.962

5.  Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.

Authors:  J C Boothroyd; C A Paynter; G A Cross; A Bernards; P Borst
Journal:  Nucleic Acids Res       Date:  1981-09-25       Impact factor: 16.971

6.  The ovalbumin gene-sequence of putative control regions.

Authors:  C Benoist; K O'Hare; R Breathnach; P Chambon
Journal:  Nucleic Acids Res       Date:  1980-01-11       Impact factor: 16.971

7.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

8.  Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.

Authors:  A van Ooyen; J van den Berg; N Mantei; C Weissmann
Journal:  Science       Date:  1979-10-19       Impact factor: 47.728

9.  The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei.

Authors:  J H Hoeijmakers; P Borst; J van den Burg; C Weissmann; G A Cross
Journal:  Gene       Date:  1980-03       Impact factor: 3.688

10.  Novel expression-linked copies of the genes for variant surface antigens in trypanosomes.

Authors:  J H Hoeijmakers; A C Frasch; A Bernards; P Borst; G A Cross
Journal:  Nature       Date:  1980-03-06       Impact factor: 49.962
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  20 in total

1.  Analysis of a donor gene region for a variant surface glycoprotein and its expression site in African trypanosomes.

Authors:  D J LaCount; N M El-Sayed; S Kaul; D Wanless; C M Turner; J E Donelson
Journal:  Nucleic Acids Res       Date:  2001-05-15       Impact factor: 16.971

Review 2.  The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes.

Authors:  David Horn; J David Barry
Journal:  Chromosome Res       Date:  2005       Impact factor: 5.239

Review 3.  Molecular biology of trypanosome antigenic variation.

Authors:  J E Donelson; A C Rice-Ficht
Journal:  Microbiol Rev       Date:  1985-06

Review 4.  [African trypanosomes: parasites with protective mechanisms].

Authors:  H J Risse
Journal:  Naturwissenschaften       Date:  1988-10

5.  Structure and transcription of a telomeric surface antigen gene of Trypanosoma brucei.

Authors:  A Bernards; J M Kooter; P Borst
Journal:  Mol Cell Biol       Date:  1985-03       Impact factor: 4.272

6.  Reverse transcription of trypanosome variable antigen mRNAs initiated by a specific oligonucleotide primer.

Authors:  S C Merritt; C Tschudi; W H Konigsberg; F F Richards
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

7.  Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei.

Authors:  L H Van der Ploeg; A Bernards; F A Rijsewijk; P Borst
Journal:  Nucleic Acids Res       Date:  1982-01-22       Impact factor: 16.971

8.  An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome.

Authors:  L H Van der Ploeg; D Valerio; T De Lange; A Bernards; P Borst; F G Grosveld
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

9.  Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure.

Authors:  M Seiki; S Hattori; M Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

10.  Structure and expression of a Trypanosoma brucei gambiense variant specific antigen gene.

Authors:  E Pays; M Lheureux; M Steinert
Journal:  Nucleic Acids Res       Date:  1982-05-25       Impact factor: 16.971
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