Literature DB >> 3858818

Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein.

J D Bangs, D Hereld, J L Krakow, G W Hart, P T Englund.   

Abstract

The variant surface glycoprotein of the parasite Trypanosoma brucei contains a glycolipid of unknown structure covalently attached to its COOH terminus. We have shown, by using metabolic labeling with [35S]methionine or [3H]myristic acid, precipitation with specific antibodies, and NaDodSO4/polyacrylamide gel electrophoresis, that this glycolipid is attached to the variant surface glycoprotein polypeptide within 1 min after its translation.

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Year:  1985        PMID： 3858818      PMCID： PMC397744          DOI： 10.1073/pnas.82.10.3207

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  30 in total

1.  A simplified method for cyanogen bromide activation of agarose for affinity chromatography.

Authors:  S C March; I Parikh; P Cuatrecasas
Journal:  Anal Biochem       Date:  1974-07       Impact factor: 3.365

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.

Authors:  J C Boothroyd; C A Paynter; G A Cross; A Bernards; P Borst
Journal:  Nucleic Acids Res       Date:  1981-09-25       Impact factor: 16.971

4.  Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

Authors:  S M Lanham; D G Godfrey
Journal:  Exp Parasitol       Date:  1970-12       Impact factor: 2.011

5.  Immunological purification and partial characterization of variant-specific surface antigen messenger RNA of Trypanosoma brucei brucei.

Authors:  M Lheureux; M Lheureux; T Vervoort; N Van Meirvenne; M Steinert
Journal:  Nucleic Acids Res       Date:  1979-10-10       Impact factor: 16.971

6.  A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic 'tail' absent from purified glycoprotein.

Authors:  J C Boothroyd; G A Cross; J H Hoeijmakers; P Borst
Journal:  Nature       Date:  1980-12-11       Impact factor: 49.962

7.  Glycopeptides from variant surface glycoproteins of Trypanosoma Brucei. C-terminal location of antigenically cross-reacting carbohydrate moieties.

Authors:  A A Holder; G A Cross
Journal:  Mol Biochem Parasitol       Date:  1981-02       Impact factor: 1.759

8.  Trypanosoma brucei brucei: inhibition of glycosylation of the major variable surface coat glycoprotein by tunicamycin.

Authors:  J E Strickler; C L Patton
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

9.  Studies on the biosynthesis of the variant surface glycoproteins of Trypanosoma brucei: sequence of glycosylation.

Authors:  L Rovis; D K Dube
Journal:  Mol Biochem Parasitol       Date:  1981-11       Impact factor: 1.759

10.  On the surface coat and flagellar adhesion in trypanosomes.

Authors:  K Vickerman
Journal:  J Cell Sci       Date:  1969-07       Impact factor: 5.285
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  76 in total

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Authors:  Adrian R Walmsley; Nigel M Hooper
Journal:  Biochem J       Date:  2003-02-15       Impact factor: 3.857

2.  Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion.

Authors:  J D Bangs; D M Ransom; M A McDowell; E M Brouch
Journal:  EMBO J       Date:  1997-07-16       Impact factor: 11.598

3.  Unfolded Protein Response Pathways in Bloodstream-Form Trypanosoma brucei?

Authors:  Calvin Tiengwe; Abigail E N A Brown; James D Bangs
Journal:  Eukaryot Cell       Date:  2015-08-28

4.  Characterization of the phosphatidylinositol-glycan membrane anchor of human placental alkaline phosphatase.

Authors:  A D Howard; J Berger; L Gerber; P Familletti; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

5.  De novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes.

Authors:  Shaheen S Sutterwala; Caleb H Creswell; Sumana Sanyal; Anant K Menon; James D Bangs
Journal:  Eukaryot Cell       Date:  2007-01-12

6.  Anti-inositolglycan antibodies selectively block some of the actions of insulin in intact BC3H1 cells.

Authors:  G Romero; G Gámez; L C Huang; K Lilley; L Luttrell
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

Review 7.  Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor.

Authors:  M P Lisanti; E Rodriguez-Boulan; A R Saltiel
Journal:  J Membr Biol       Date:  1990-07       Impact factor: 1.843

8.  A passion for parasites.

Authors:  Paul T Englund
Journal:  J Biol Chem       Date:  2014-10-21       Impact factor: 5.157

9.  GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK.

Authors:  Sungjin Park; Changhee Lee; Priyanka Sabharwal; Mei Zhang; Caren L Freel Meyers; Shanthini Sockanathan
Journal:  Science       Date:  2013-01-18       Impact factor: 47.728

10.  The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols.

Authors:  T L Doering; M S Pessin; G W Hart; D M Raben; P T Englund
Journal:  Biochem J       Date:  1994-05-01       Impact factor: 3.857
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