Literature DB >> 6271097

Persistent reactivable latent herpes simplex virus infection in trigeminal ganglia of mice treated with antiviral drugs.

B Svennerholm, A Vahlne, E Lycke.   

Abstract

Latent reactivable infection was established with HSV in mouse trigeminal ganglion. A number of antiviral drugs (IUDR, acycloguanosine, Ara-A, PAA and PFA), effective against acute CNS infection with HSV, failed to influence the latent infection once established. Neither lipophilic properties of PFA-derivatives nor the combination of Ara-A and acycloguanosine improved the drug-effects on HSV latency.

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Year:  1981        PMID： 6271097     DOI： 10.1007/bf01315264

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  16 in total

1.  Efficacy of phosphonoacetic acid on herpes simplex virus infection of sensory ganglia.

Authors:  C R Wohlenberg; M A Walz; A L Notkins
Journal:  Infect Immun       Date:  1976-05       Impact factor: 3.441

2.  Phosphonoacetic acid-resistant herpes simplex virus infection in hairless mice.

Authors:  R J Klein; A E Friedman-Kien
Journal:  Antimicrob Agents Chemother       Date:  1975-03       Impact factor: 5.191

3.  Orofacial herpes simplex virus infection in hairless mice: latent virus in trigeminal ganglia after topical antiviral treatment.

Authors:  R J Klein; A E Friedman-Kien; P B Yellin
Journal:  Infect Immun       Date:  1978-04       Impact factor: 3.441

4.  Therapeutic effect of trisodium phosphonoformate on cutaneous herpesvirus infection in guinea pigs.

Authors:  S Alenius; Z Dinter; B Oberg
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

5.  Latent herpes simplex virus in spinal ganglia of mice.

Authors:  J G Stevens; M L Cook
Journal:  Science       Date:  1971-08-27       Impact factor: 47.728

6.  Spread of herpes simplex virus in peripheral nerves.

Authors:  K Kristensson; E Lycke; J Sjöstrand
Journal:  Acta Neuropathol       Date:  1971       Impact factor: 17.088

7.  Subtyping of herpes simplex virus.

Authors:  A Vahlne; J Blomberg; S Olofsson; E Lycke
Journal:  Acta Pathol Microbiol Scand B       Date:  1975-10

8.  Herpetic ganglionic latency. Aciclovir and vidarabine therapy.

Authors:  D Pavan-Langston; N H Park; J H Lass
Journal:  Arch Ophthalmol       Date:  1979-08

Review 9.  Treatment of infections due to Herpesvirus in humans: a critical review of the state of the art.

Authors:  C A Alford; R J Whitley
Journal:  J Infect Dis       Date:  1976-06       Impact factor: 5.226

10.  Effect of acycloguanosine treatment of acute and latent herpes simplex infections in mice.

Authors:  H J Field; S E Bell; G B Elion; A A Nash; P Wildy
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191
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  6 in total

1.  Amplification of herpes simplex virus resistance in mouse neuroblastoma (Cl300) cells.

Authors:  E Nilheden; S Jeansson; A Vahlne
Journal:  Arch Virol       Date:  1985       Impact factor: 2.574

Review 2.  The pathogenesis of acute, latent and recurrent herpes simplex virus infections.

Authors:  R J Klein
Journal:  Arch Virol       Date:  1982       Impact factor: 2.574

3.  Neuritic uptake and transport of antiviral drugs modifying herpes simplex virus infection of rat sensory neurons.

Authors:  B Svennerholm; R Ziegler; E Lycke
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574

4.  Effect of discontinuous acyclovir treatment on in vitro reactivation of herpes simplex virus from latently infected trigeminal ganglia.

Authors:  R J Klein; A E Friedman-Kien; E DeStefano
Journal:  Antimicrob Agents Chemother       Date:  1983-07       Impact factor: 5.191

5.  Effects of prolonged cultivation in the presence of acyclovir on recovery of latent herpes simplex virus from human trigeminal ganglia.

Authors:  M E Lewis; K G Warren; V M Jeffrey; D L Tyrrell
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191

6.  Efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine against primary and recrudescent genital herpes simplex virus type 2 infections in guinea pigs.

Authors:  E B Fraser-Smith; D F Smee; T R Matthews
Journal:  Antimicrob Agents Chemother       Date:  1983-12       Impact factor: 5.191
  6 in total

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