Literature DB >> 166611

Phosphonoacetic acid-resistant herpes simplex virus infection in hairless mice.

R J Klein, A E Friedman-Kien.   

Abstract

Phosphonoacetic acid (PAA)-resistant type 1 herpes simplex virus population was isolated by repeated passage of the virus in the presence of this inhibitor. Hairless mice infected percutaneously with the inhibitor-resistant or the parental inhibitor-susceptible virus were treated intraperitoneally with PAA and 9-beta-d-arabinofuranosyl-adenine by using several different dosage schedules. Whereas 9-beta-d-arabinofuranosyl-adenine was effective both in the PAA-susceptible and PAA-resistant herpes simplex virus-induced skin infection, PAA suppressed only the infection induced by the parental PAA-susceptible virus.

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Year:  1975        PMID： 166611      PMCID： PMC429126          DOI： 10.1128/AAC.7.3.289

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  CELL CULTURE STUDIES ON ANTIVIRAL AGENTS. I. ACTION OF CYTOSINE ARABINOSIDE AND SOME COMPARISONS WITH 5-IODO-2-DEOXYURIDINE.

Authors:  D A BUTHALA
Journal:  Proc Soc Exp Biol Med       Date:  1964-01

2.  Adenine arabinoside effect on experimental idoxuridine-resistant herpes simplex infection.

Authors:  A B Nesburn; C Robinson; R Dickinson
Journal:  Invest Ophthalmol       Date:  1974-04

3.  Chemotherapy of cutaneous herpesvirus infection of hairless mice.

Authors:  M Lieberman; T W Schafer; P E Came
Journal:  J Invest Dermatol       Date:  1973-04       Impact factor: 8.551

4.  A double blind clinical study of adenine arabinoside therapy of viral keratoconjunctivitis.

Authors:  D Pavan-Langston; C H Dohlman
Journal:  Am J Ophthalmol       Date:  1972-07       Impact factor: 5.258

5.  Herpes simplex virus infection of the cornea.

Authors:  D O White; M A Shew; K G Howsam; I F Robertson
Journal:  Med J Aust       Date:  1968-07-13       Impact factor: 7.738

6.  Development of resistance to antiviral drugs.

Authors:  H E Renis; D A Buthala
Journal:  Ann N Y Acad Sci       Date:  1965-07-30       Impact factor: 5.691

7.  Herpes simplex virus skin infection in hairless mice: treatment with antiviral compounds.

Authors:  R J Klein; A E Friedman-Kien; E Brady
Journal:  Antimicrob Agents Chemother       Date:  1974-03       Impact factor: 5.191

8.  Suppression of herpes simplex virus infection by phosphonoacetic acid.

Authors:  N L Shipkowitz; R R Bower; R N Appell; C W Nordeen; L R Overby; W R Roderick; J B Schleicher; A M Von Esch
Journal:  Appl Microbiol       Date:  1973-09

9.  The antiviral activity of 9-beta-D-arabinofuranosyladenine (ARA-A).

Authors:  F M Schabel
Journal:  Chemotherapia (Basel)       Date:  1968

10.  Treatment of herpes simplex virus types 1 and 2 encephalitis in mice with 9-beta-D-arabinofuranosyladenine.

Authors:  B J Sloan; F A Miller; I W McLean
Journal:  Antimicrob Agents Chemother       Date:  1973-01       Impact factor: 5.191
  10 in total
  26 in total

1.  Isolation of herpes simplex virus clones and drug resistant mutants in microcultures.

Authors:  R J Klein
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

2.  Differential effect of phosphonoacetic acid on the expression of Epstein-Barr viral antigens and virus production.

Authors:  O Nyormoi; D A Thorley-Lawson; J Elkington; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

3.  Phosphonoacetic acid in the treatment of experimental ocular herpes simplex infections.

Authors:  R F Meyer; E D Varnell; H E Kaufman
Journal:  Antimicrob Agents Chemother       Date:  1976-02       Impact factor: 5.191

4.  Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site.

Authors:  R J Klein; A E Friedman-Kien; E Brady
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

5.  Latent herpes simplex virus infections in sensory ganglia of mice after topical treatment with adenine arabinoside and adenine arabinoside monophosphate.

Authors:  R J Klein; A E Friedman-Kien
Journal:  Antimicrob Agents Chemother       Date:  1977-11       Impact factor: 5.191

6.  Pathogenetic mechansims of recurrent herpes simplex virus infections.

Authors:  R J Klein
Journal:  Arch Virol       Date:  1976       Impact factor: 2.574

7.  Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.

Authors:  H J Field; D M Coen
Journal:  J Virol       Date:  1986-10       Impact factor: 5.103

8.  Gastrointestinal invasion by herpes simplex virus type 1 inoculated cutaneously into the immunosuppressed mice.

Authors:  H Takase; E Yamamura; Y Murakami; T Ikeuchi; Y Osada
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

9.  Experimental skin infection with an acyclovir resistant herpes simplex virus mutant: response to antiviral treatment and protection against reinfection.

Authors:  R J Klein; E DeStefano; E Brady; A E Friedman-Kien
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

10.  Inhibition of herpesvirus multiplication in guinea pig skin by antiviral compounds.

Authors:  S Alenius
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574
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