Literature DB >> 6271053

Selective inhibition of herpesvirus deoxyribonucleic acid synthesis by acycloguanosine, 2'-fluoro-5-iodo-aracytosine, and (E)-5-(2-bromovinyl)-2'-deoxyuridine.

A Larsson, B Oberg.   

Abstract

The selectivity of inhibition of herpesvirus deoxyribonucleic acid synthesis by acycloguanosine, 2'-fluoro-5-iodo-aracytosine, and (E)-5-(2-bromovinyl)-2'-deoxyuridine was determined by isopycnic banding of (32)P-labeled deoxyribonucleic acid from herpesvirus-infected and uninfected cells.

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Year:  1981        PMID: 6271053      PMCID: PMC181545          DOI: 10.1128/AAC.19.5.927

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  10 in total

1.  Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.

Authors:  G B Elion; P A Furman; J A Fyfe; P de Miranda; L Beauchamp; H J Schaeffer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

2.  2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.

Authors:  C Lopez; K A Watanabe; J J Fox
Journal:  Antimicrob Agents Chemother       Date:  1980-05       Impact factor: 5.191

3.  9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.

Authors:  H J Schaeffer; L Beauchamp; P de Miranda; G B Elion; D J Bauer; P Collins
Journal:  Nature       Date:  1978-04-13       Impact factor: 49.962

4.  Nucleoside analogs with antiviral activity.

Authors:  W H Prusoff; D C Ward
Journal:  Biochem Pharmacol       Date:  1976-06-01       Impact factor: 5.858

5.  Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

Authors:  K A Watanabe; U Reichman; K Hirota; C Lopez; J J Fox
Journal:  J Med Chem       Date:  1979-01       Impact factor: 7.446

6.  The selective inhibition of viral DNA synthesis by chemotherapeutic agents: an indicator of clinical usefulness?

Authors:  J C Drach; C Shipman
Journal:  Ann N Y Acad Sci       Date:  1977-03-04       Impact factor: 5.691

Review 7.  Enzymatic targets in virus chemotherapy.

Authors:  E Helgstrand; B Oberg
Journal:  Antibiot Chemother (1971)       Date:  1980

8.  Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate.

Authors:  P A Furman; M H St Clair; J A Fyfe; J L Rideout; P M Keller; G B Elion
Journal:  J Virol       Date:  1979-10       Impact factor: 5.103

9.  (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Authors:  E De Clercq; J Descamps; P De Somer; P J Barr; A S Jones; R T Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

10.  Characteristics of herpesvirus mutants resistant to phosphonoformate and phosphonoacetate.

Authors:  B Eriksson; B Oberg
Journal:  Antimicrob Agents Chemother       Date:  1979-06       Impact factor: 5.191

  10 in total
  4 in total

1.  Thymidine plaque autoradiography of thymidine kinase-positive and thymidine kinase-negative herpesviruses.

Authors:  R B Tenser; J C Jones; S J Ressel; F A Fralish
Journal:  J Clin Microbiol       Date:  1983-01       Impact factor: 5.948

2.  Effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine on synthesis of herpes simplex virus type 1-specific polypeptides.

Authors:  S A Siegel; M J Otto; E De Clercq; W H Prusoff
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191

3.  Modified polynucleotides. VI. Properties of a synthetic DNA containing the anti-herpes agent (E)-5-(2-bromovinyl)-2'-deoxyuridine.

Authors:  J Sági; A Czuppon; M Kajtár; A Szabolcs; A Szemzö; L Otvös
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

4.  9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication.

Authors:  A Larsson; B Oberg; S Alenius; C E Hagberg; N G Johansson; B Lindborg; G Stening
Journal:  Antimicrob Agents Chemother       Date:  1983-05       Impact factor: 5.191

  4 in total

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