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Literature DB >> 6255427

Histone 2B can be modified by the attachment of ubiquitin.

Abstract

Histone 2B in mouse and man can be modified by the post-translational addition of ubiquitin. In mouse L1210 cells, both H2B variants are modified, however only to the extent of 1-1.5% compared with about 11% of H2A. Analysis of cyanogen bromide peptides shows that ubiquitin is attached to the C-terminal part of the histone.

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Year: 1980 PMID： 6255427 PMCID： PMC324378 DOI： 10.1093/nar/8.20.4671

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

5 in total

1. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors: W M Bonner; R A Laskey
Journal: Eur J Biochem Date: 1974-07-01

2. Non-allelic variants of histones 2a, 2b and 3 in mammals.

Authors: S G Franklin; A Zweidler
Journal: Nature Date: 1977-03-17 Impact factor: 49.962

3. Resolution of histones by polyacrylamide gel electrophoresis in presence of nonionic detergents.

Authors: A Zweidler
Journal: Methods Cell Biol Date: 1978 Impact factor: 1.441

4. Two-dimensional gel analysis of histones in acid extracts of nuclei, cells, and tissues.

Authors: W M Bonner; M H West; J D Stedman
Journal: Eur J Biochem Date: 1980-08

5. Histone 2A, a heteromorphous family of eight protein species.

Authors: M H West; W M Bonner
Journal: Biochemistry Date: 1980-07-08 Impact factor: 3.162

5 in total

79 in total

1. Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

Authors: Cheng-Fu Kao; Cory Hillyer; Toyoko Tsukuda; Karl Henry; Shelley Berger; Mary Ann Osley
Journal: Genes Dev Date: 2004-01-15 Impact factor: 11.361

Review 2. Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.

Authors: Mahesh B Chandrasekharan; Fu Huang; Zu-Wen Sun
Journal: Epigenetics Date: 2010-08-16 Impact factor: 4.528

Histone 2B can be modified by the attachment of ubiquitin.

1. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

2. Non-allelic variants of histones 2a, 2b and 3 in mammals.

3. Resolution of histones by polyacrylamide gel electrophoresis in presence of nonionic detergents.

4. Two-dimensional gel analysis of histones in acid extracts of nuclei, cells, and tissues.

5. Histone 2A, a heteromorphous family of eight protein species.

1. Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

Review 2. Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.

3. Ubiquitinated proteins including uH2A on the human and mouse inactive X chromosome: enrichment in gene rich bands.

4. Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones.

5. Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53.

Review 6. The role of deubiquitinating enzymes in chromatin regulation.

7. Association of ubiquitin-activating enzyme with HeLa cell chromosomes during mitosis.

8. Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation.

Review 9. The epigenetics of adult (somatic) stem cells.

10. Histone modifications in Trypanosoma brucei.