Literature DB >> 6246500

Probable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons.

S Kimura, R V Lewis, A S Stern, J Rossier, S Stein, S Udenfriend.   

Abstract

Adrenal chromaffin granules contain at least 10 peptides, ranging in size from 3 to 5 kilodaltons, that yield, upon digestion with trypsin, peptides that show specific binding to opiate receptors. All are distinctly different from beta-endorphin. Two of these peptides have been purified to homogeneity and subjected to chemical analysis. One is apparently a [Met]enkephalin precursor containing two copies of the [Met]enkephalin sequence. The other peptide contains both [Leu]enkephalin and [Met]enkephalin sequences and is presumably a common precursor of the two forms of enkephalin.

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Year:  1980        PMID： 6246500      PMCID： PMC348561          DOI： 10.1073/pnas.77.3.1681

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  Automatic Monitoring of primary amines in preparative column effluents with fluorescamine.

Authors:  P Böhlen; S Stein; J Stone; S Udenfriend
Journal:  Anal Biochem       Date:  1975-08       Impact factor: 3.365

2.  Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.

Authors:  C H Li; D Chung
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

3.  Binding assay for opioid peptides with neuroblastoma x glioma hybrid cells: specificity of the receptor site.

Authors:  L D Gerber; S Stein; M Rubinstein; J Wideman; S Udenfriend
Journal:  Brain Res       Date:  1978-07-28       Impact factor: 3.252

4.  High-performance liquid chromatography of amino acid derivatives.

Authors:  C L Zimmerman; J J Pisano
Journal:  Methods Enzymol       Date:  1977       Impact factor: 1.600

5.  Improved manual sequencing methods.

Authors:  G E Tarr
Journal:  Methods Enzymol       Date:  1977       Impact factor: 1.600

6.  High molecular weight opioid-containing proteins in striatum.

Authors:  R V Lewis; S Stein; L D Gerber; M Rubinstein; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

7.  Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla.

Authors:  M Schultzberg; J M Lundberg; T Hökfelt; L Terenius; J Brandt; R P Elde; M Goldstein
Journal:  Neuroscience       Date:  1978       Impact factor: 3.590

8.  alpha-Neo-endorphin : a "big" Leu-enkephalin with potent opiate activity from porcine hypothalami.

Authors:  K Kangawa; H Matsuo
Journal:  Biochem Biophys Res Commun       Date:  1979-01-15       Impact factor: 3.575

9.  Detection of two endorphin-like peptides in nucleus caudatus.

Authors:  H Y Yang; W Fratta; J S Hong; A M DiGiulio; E Costa
Journal:  Neuropharmacology       Date:  1978-06       Impact factor: 5.250

10.  Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary.

Authors:  J Rossier; T M Vargo; S Minick; N Ling; F E Bloom; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205
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  17 in total

1.  Secondary structure characteristics of proenkephalin peptides E, B, and F.

Authors:  H J Hiddinga; G E Katzenstein; C R Middaugh; R V Lewis
Journal:  Neurochem Res       Date:  1990-04       Impact factor: 3.996

2.  Changes in plasma proenkephalin peptide F and catecholamine levels during graded exercise in men.

Authors:  W J Kraemer; B Noble; B Culver; R V Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

3.  Immunohistochemical localisation of substances reactive to antisera against alpha- and beta-endorphin and met-enkephalin in the brain of Rana temporaria L.

Authors:  J Doerr-Schott; M P Dubois; C Lichte
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

4.  Extracts from the brains of hibernating and alert ground squirrels: effects on cells in culture.

Authors:  D A Amorese; H Swan; J R Bamburg
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

5.  A highly potent 3200-dalton adrenal opioid peptide that contains both a [Met]- and [Leu]enkephalin sequence.

Authors:  D L Kilpatrick; T Taniguchi; B N Jones; A S Stern; J E Shively; J Hullihan; S Kimura; S Stein; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

6.  Opioid peptides as neuroregulators: potential areas for the study of genetic-behavioral mechanisms.

Authors:  J D Barchas; S Sullivan
Journal:  Behav Genet       Date:  1982-02       Impact factor: 2.805

7.  Enkephalin biosynthetic pathway: a 5300-dalton adrenal polypeptide that terminates at its COOH end with the sequence [Met]enkephalin-Arg-Gly-Leu-COOH.

Authors:  B N Jones; J E Shively; D L Kilpatrick; K Kojima; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

8.  An 18,200-dalton adrenal protein that contains four [Met]enkephalin sequences.

Authors:  D L Kilpatrick; B N Jones; R V Lewis; A S Stern; K Kojima; J E Shively; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

9.  Appearance of enkephalin-immunoreactivity in rat adrenal medulla following treatment with nicotinic antagonists or reserpine.

Authors:  M C Bohn; J A Kessler; L Golightly; I B Black
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249

10.  Isolation, structure, biological characterization, and synthesis of beta-[Tyr9]melanotropin-(9-18) decapeptide from pig hypothalami.

Authors:  A V Schally; R C Chang; W Y Huang; D H Coy; A J Kastin; T W Redding
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205
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