Literature DB >> 6245250

Early events after infection of Escherichia coli by bacteriophage T5. III. Inhibition of uracil-DNA glycosylase activity.

H R Warner, L K Johnson, D P Snustad.   

Abstract

The activity of uracil-DNA glycosylase in Escherichia coli decreases dramatically to less than 10% of its original level after infection of the cells by phage T5. Phage-induced protein synthesis is required for this inhibition to occur, and the inhibition is induced by a mutant capable of injecting only the first 8% of its DNA. The inhibitor activity in extracts of infected cells is heat labile and nondialyzable, and will inhibit enzyme activity present in extracts of uninfected cells.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6245250      PMCID： PMC288568     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

1.  Early events after infection of Escherichia coli by bacteriophage T5. Induction of a 5'-nucleotidase activity and excretion of free bases.

Authors:  H R Warner; R F Drong; S M Berget
Journal:  J Virol       Date:  1975-02       Impact factor: 5.103

2.  Deoxyuridine triphosphatase of Escherichia coli. Purification, properties, and use as a reagent to reduce uracil incorporation into DNA.

Authors:  J Shlomai; A Kornberg
Journal:  J Biol Chem       Date:  1978-05-10       Impact factor: 5.157

3.  Pre-early polypeptides of bacteriophages T5 and BF23.

Authors:  D J McCorquodale; A R Shaw; P K Shaw; G Chinnadurai
Journal:  J Virol       Date:  1977-05       Impact factor: 5.103

4.  Isolation and partial characterization of bacteriophage T5 mutants deficient in the ability to induce deoxynucleoside monophosphate kinase.

Authors:  S M Berget; H R Warner; D J McCorquodale
Journal:  J Virol       Date:  1974-07       Impact factor: 5.103

5.  The chromosome of bacteriophage T5. I. Analysis of the single-stranded DNA fragments by agarose gel electrophoresis.

Authors:  G S Hayward; M G Smith
Journal:  J Mol Biol       Date:  1972-02-14       Impact factor: 5.469

6.  Genetic and physiological studies of bacteriophage t5 I. An expanded genetic map of t5.

Authors:  H E Hendrickson; D J McCorquodale
Journal:  J Virol       Date:  1971-05       Impact factor: 5.103

7.  Enzymatic degradation of uracil-containing DNA. II. Evidence for N-glycosidase and nuclease activities in unfractionated extracts of Bacillus subtilis.

Authors:  J Duncan; L Hamilton; E C Friedberg
Journal:  J Virol       Date:  1976-08       Impact factor: 5.103

8.  Escherichia coli K-12 mutants deficient in uracil-DNA glycosylase.

Authors:  B K Duncan; P A Rockstroh; H R Warner
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

9.  Metabolism of uracil-containing DNA: degradation of bacteriophage PBS2 DNA in Bacillus subtilis.

Authors:  B K Duncan; H R Warner
Journal:  J Virol       Date:  1977-06       Impact factor: 5.103

10.  The properties of a bacteriophage T5 mutant unable to induce deoxyuridine 5'-triphosphate nucleotidohydrolase. Synthesis of uracil-containing T5 deoxyribonucleic acid.

Authors:  H R Warner; R B Thompson; T J Mozer; B K Duncan
Journal:  J Biol Chem       Date:  1979-08-25       Impact factor: 5.157
View more
  8 in total

1.  Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands.

Authors:  Prem Singh Kaushal; Ramappa K Talawar; Umesh Varshney; M Vijayan
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-07-27

Review 2.  Mutagenesis after exposure of bacteria to ultraviolet light and delayed photoreversal.

Authors:  B A Bridges
Journal:  Mol Gen Genet       Date:  1992-06

3.  Overexpression, purification, crystallization and preliminary X-ray analysis of uracil N-glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor.

Authors:  Prem Singh; Ramappa K Talawar; P D V Krishna; Umesh Varshney; M Vijayan
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-11-30

4.  Uracil-DNA glycosylase inhibitor of bacteriophage PBS2: cloning and effects of expression of the inhibitor gene in Escherichia coli.

Authors:  Z Wang; D W Mosbaugh
Journal:  J Bacteriol       Date:  1988-03       Impact factor: 3.490

5.  Use of a molecular beacon based fluorescent method for assaying uracil DNA glycosylase (Ung) activity and inhibitor screening.

Authors:  Avani Mehta; Prateek Raj; Sandeep Sundriyal; Balasubramanian Gopal; Umesh Varshney
Journal:  Biochem Biophys Rep       Date:  2021-02-15

6.  A phage mechanism for selective nicking of dUMP-containing DNA.

Authors:  Tridib Mahata; Shahar Molshanski-Mor; Moran G Goren; Biswanath Jana; Miriam Kohen-Manor; Ido Yosef; Oren Avram; Tal Pupko; Dor Salomon; Udi Qimron
Journal:  Proc Natl Acad Sci U S A       Date:  2021-06-08       Impact factor: 11.205

7.  Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase.

Authors:  Ambrose R Cole; Sapir Ofer; Ksenia Ryzhenkova; Gediminas Baltulionis; Peter Hornyak; Renos Savva
Journal:  Nucleic Acids Res       Date:  2013-07-26       Impact factor: 16.971

Review 8.  DNA-Binding Proteins Essential for Protein-Primed Bacteriophage Φ29 DNA Replication.

Authors:  Margarita Salas; Isabel Holguera; Modesto Redrejo-Rodríguez; Miguel de Vega
Journal:  Front Mol Biosci       Date:  2016-08-05
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.