Literature DB >> 406424

Metabolism of uracil-containing DNA: degradation of bacteriophage PBS2 DNA in Bacillus subtilis.

B K Duncan, H R Warner.   

Abstract

When Bacillus subtilis is infected by the uracil-containing DNA phage PBS2, the parental DNA labeled with radioactive uracil and cytosine remains acid insoluble. If the synthesis of the phage-induced uracil-DNA N-glycosidase inhibitor is prevented, the parental DNA is completely degraded to acid-soluble products beginning at about 6 min after infection. The host N-glycosidase probably initiates the degradation pathway, with nucleases being responsible for the remaining degradation of the DNA.

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Year:  1977        PMID： 406424      PMCID： PMC515785     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  14 in total

1.  Replacement of thymidylic acid by deoxyuridylic acid in the deoxyribonucleic acid of a transducing phage for Bacillus subtilis.

Authors:  I TAKAHASHI; J MARMUR
Journal:  Nature       Date:  1963-02-23       Impact factor: 49.962

2.  Early events after infection of Escherichia coli by bacteriophage T5. Induction of a 5'-nucleotidase activity and excretion of free bases.

Authors:  H R Warner; R F Drong; S M Berget
Journal:  J Virol       Date:  1975-02       Impact factor: 5.103

3.  ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. III. THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID.

Authors:  M J Bessman; I R Lehman; J Adler; S B Zimmerman; E S Simms; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1958-07-15       Impact factor: 11.205

4.  Deoxythymidylate phosphohydrolase induced by bacteriophage PBS2 during infection of Bacillus subtilis.

Authors:  A R Price; S M Fogt
Journal:  J Biol Chem       Date:  1973-02-25       Impact factor: 5.157

Review 5.  First-step-transfer deoxyribonucleic acid of bacteriophage T5.

Authors:  Y T Lanni
Journal:  Bacteriol Rev       Date:  1968-09

6.  New class of enzymes acting on damaged DNA.

Authors:  T Lindahl
Journal:  Nature       Date:  1976 Jan 1-8       Impact factor: 49.962

7.  Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.

Authors:  B K Tye; P O Nyman; I R Lehman; S Hochhauser; B Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1977-01       Impact factor: 11.205

8.  Bacteriophage PBS2-induced inhibition of uracil-containing DNA degradation.

Authors:  G E Katz; A R Price; M J Pomerantz
Journal:  J Virol       Date:  1976-11       Impact factor: 5.103

9.  New deoxyribonucleic acid polymerase induced by Bacillus subtilis bacteriophage PBS2.

Authors:  A R Price; S J Cook
Journal:  J Virol       Date:  1972-04       Impact factor: 5.103

10.  An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues.

Authors:  T Lindahl
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205
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  7 in total

1.  Isolation and partial characterization of a bacteriophage T5 mutant unable to induce thymidylate synthetase and its use in studying the effect of uracil incorporation into DNA on early gene expression.

Authors:  W J Swart; H R Warner
Journal:  J Virol       Date:  1985-04       Impact factor: 5.103

2.  Escherichia coli K-12 mutants deficient in uracil-DNA glycosylase.

Authors:  B K Duncan; P A Rockstroh; H R Warner
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

3.  Early events after infection of Escherichia coli by bacteriophage T5. III. Inhibition of uracil-DNA glycosylase activity.

Authors:  H R Warner; L K Johnson; D P Snustad
Journal:  J Virol       Date:  1980-01       Impact factor: 5.103

4.  Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases.

Authors:  Béata G Vértessy; Judit Tóth
Journal:  Acc Chem Res       Date:  2009-01-20       Impact factor: 22.384

5.  Isolation of insertion, deletion, and nonsense mutations of the uracil-DNA glycosylase (ung) gene of Escherichia coli K-12.

Authors:  B K Duncan
Journal:  J Bacteriol       Date:  1985-11       Impact factor: 3.490

6.  Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.

Authors:  Villő Muha; András Horváth; Angéla Békési; Mária Pukáncsik; Barbara Hodoscsek; Gábor Merényi; Gergely Róna; Júlia Batki; István Kiss; Ferenc Jankovics; Péter Vilmos; Miklós Erdélyi; Beáta G Vértessy
Journal:  PLoS Genet       Date:  2012-06-07       Impact factor: 5.917

7.  Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase.

Authors:  Ambrose R Cole; Sapir Ofer; Ksenia Ryzhenkova; Gediminas Baltulionis; Peter Hornyak; Renos Savva
Journal:  Nucleic Acids Res       Date:  2013-07-26       Impact factor: 16.971
  7 in total

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