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Literature DB >> 6217448

Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA.

Abstract

Antibodies raised in rabbits against deoxyguanylate and deoxycytidylate bind to 3H-lambda double stranded DNA and the binding is base specific. The concentrations of antibody populations that bind to double stranded DNA are much less than those binding to denatured DNA. Due to their low concentrations, these antibodies were not detected in earlier studies. These antibodies are expected to be useful to probe the conformational flexibilities of double stranded DNAs.

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Year: 1982 PMID： 6217448 PMCID： PMC326917 DOI： 10.1093/nar/10.20.6273

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

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References

11 in total

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10. Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC).poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations.

Authors: R M Santella; D Grunberger; S Broyde; B E Hingerty
Journal: Nucleic Acids Res Date: 1981-10-24 Impact factor: 16.971

Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA.

1. Purification and further properties of single-strand-specific nuclease from Aspergillus oryzae.

2. Colicin E1 plasmid as a probe for detection and study of anti-dna activity in SLE sera.

3. Antibodies specific to deoxyguanosine 5'-phosphate.

4. DNA structure and gene regulation.

5. Immunologic studies on nucleic acids and their components. I. An analysis of the specificity of anti-deoxyadenylate antibodies by a membrane-binding technique.

6. Specificity of deoxycytidylate antibodies.

7. Antibodies to adenosine 5'-monophosphate: purification and specificity.

8. Antibodies specific to a deoxyribodinucleotide sequence.

9. Antibodies specific to two deoxyribotrinucleotide sequences.

10. Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC).poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations.