Literature DB >> 561950

Antibodies specific to two deoxyribotrinucleotide sequences.

S A Khan, T M Jacob.   

Abstract

Antibodies to the deoxyribotrinucleotides dpApTpA and dpApApT were prepared by injecting the bovine serum albumin conjugates of the respective haptens in rabbits. The specificities of the antibodies were determined by estimating the inhibition of the binding of the tritiated haptens to the immunoglobulins by various nonradioactive mono- and oligonucleotides, using nitrocellulose membrane binding assay. Anti-dpApTpA and anti-dpApApT antisera were found to contain antibodies which were highly specific to the respective hapten sequence.

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Year:  1977        PMID： 561950      PMCID： PMC342630          DOI： 10.1093/nar/4.9.3007

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  5 in total

1.  Antibodies to the codons ApApAp, ApApC, and ApUpG.

Authors:  R M D'Alisa; B F Erlanger
Journal:  Biochemistry       Date:  1974-08-13       Impact factor: 3.162

2.  Specific antibodies to dinucleotides and trinucleotides.

Authors:  B Bonavida; S Fuchs; M Sela; P W Roddy; H A Sober
Journal:  Eur J Biochem       Date:  1972-12-18

3.  Antibodies to nucleic acids. Immunochemical studies on dinucleoside phosphate-protein conjugates.

Authors:  S P Wallace; B F Erlanger; S M Beiser
Journal:  Biochemistry       Date:  1971-02-16       Impact factor: 3.162

4.  Immunologic studies on nucleic acids and their components. I. An analysis of the specificity of anti-deoxyadenylate antibodies by a membrane-binding technique.

Authors:  M Z Humayun; T M Jacob
Journal:  Biochim Biophys Acta       Date:  1973-11-26

5.  Antibodies which react with nucleic acids.

Authors:  S M Beiser; B F Erlanger
Journal:  Cancer Res       Date:  1966-09       Impact factor: 12.701
  5 in total
  3 in total

1.  Formation and characterization of antibody against 2'-(5"-phosphoribosyl)-5' AMP, the monomer form of poly(adenosine diphosphate ribose).

Authors:  H Sakura; M Miwa; Y Kanai; T Matsushima; T Sugimura
Journal:  Nucleic Acids Res       Date:  1978-11       Impact factor: 16.971

2.  Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA.

Authors:  A Jacob; T M Jacob
Journal:  Nucleic Acids Res       Date:  1982-10-25       Impact factor: 16.971

3.  Antibodies elicited by defined oligodeoxyribonucleotide sequences.

Authors:  H J Störl; H Simon; H Barthelmes
Journal:  Nucleic Acids Res       Date:  1978-12       Impact factor: 16.971
  3 in total

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