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Literature DB >> 620719

The mitigating effect of dietary antioxidants on chemically-induced carcinogenesis.

Abstract

The effect of a dietary antioxidant mixture on 3-methylcholanthrene mediated carcinogenesis in hairless mice was investigated. The antioxidant mixture significantly reduced the frequency of premalignant lesions and their subsequent development into tumors. The similarities in response of chemical and UV light-carcinogenesis to these antioxidants suggest some congruity in the mechanisms of the carcinogenic process.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1978 PMID： 620719 DOI： 10.1007/bf01921933

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

16 in total

1. Free radical formation in the skin following exposure to ultraviolet light.

Authors: A L NORINS
Journal: J Invest Dermatol Date: 1962-11 Impact factor: 8.551

2. Role of free radicals in mutation, cancer, aging, and the maintenance of life.

Authors: D HARMAN
Journal: Radiat Res Date: 1962-05 Impact factor: 2.841

3. Prolongation of the normal lifespan and inhibition of spontaneous cancer by antioxidants.

Authors: D HARMAN
Journal: J Gerontol Date: 1961-07

4. Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats.

Authors: B M Ulland; J H Weisburger; R S Yamamoto; E K Weisburger
Journal: Food Cosmet Toxicol Date: 1973-04

5. Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by several sulfur-containing compounds.

Authors: L W Wattenberg
Journal: J Natl Cancer Inst Date: 1974-05 Impact factor: 13.506

6. Inhibition of chemical carcinogen-induced pulmonary neoplasia by butylated hydroxyanisole.

Authors: L W Wattenberg
Journal: J Natl Cancer Inst Date: 1973-06 Impact factor: 13.506

7. Inhibition of carcinogen formation in skin irradiated with ultraviolet light.

Authors: W Lo; H S Black
Journal: Nature Date: 1973 Dec 21-28 Impact factor: 49.962

8. Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by phenolic antioxidants and ethoxyquin.

Authors: L W Wattenberg
Journal: J Natl Cancer Inst Date: 1972-05 Impact factor: 13.506

9. Free radical inhibitory effect of some anticancer compounds.

Authors: K K Georgieff
Journal: Science Date: 1971-08-06 Impact factor: 47.728

Review 10. Biological antioxidant protection against lipid peroxidation damage.

Authors: A L Tappel
Journal: Am J Clin Nutr Date: 1970-08 Impact factor: 7.045

3 in total

1. Reactive oxygen in the tumor promotion stage of skin carcinogenesis.

Authors: S M Fischer; G S Cameron; J K Baldwin; D W Jasheway; K E Patrick
Journal: Lipids Date: 1988-06 Impact factor: 1.880

2. Effect of lipid soluble antioxidants on cytotoxicity induced by photochemical products of cholesterol.

Authors: J T Chan; E Y Chan; H S Black; L E Wyborny
Journal: Experientia Date: 1980-04-15

3. Differential effects of antioxidants, steroids and other compounds on benzo(a)pyrene 3-hydroxylase activity in various tissues of rat.

Authors: A D Rahimtula; P K Zachariah; P J O'Brien
Journal: Br J Cancer Date: 1979-07 Impact factor: 7.640

3 in total