Literature DB >> 5564042

Free radical inhibitory effect of some anticancer compounds.

K K Georgieff.   

Abstract

Conventional tests for polymerization initiated by free radicals indicate that alkylating agents vary in free radical inhibitory activity from negligible to moderately strong; antimetabolites from negligible to weak; hormones, steroids, and phenolics from very weak to very strong; and antibiotics from moderate to very strong. Vitamins A and C and copper, which potentiate the biological activity of some anticancer compounds, are relatively strong free radical inhibitors.

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Year:  1971        PMID: 5564042     DOI: 10.1126/science.173.3996.537

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  The mitigating effect of dietary antioxidants on chemically-induced carcinogenesis.

Authors:  J T Chan; H S Black
Journal:  Experientia       Date:  1978-01-15

2.  The reaction of hydroxyurea with oxyhaemocyanin and methaemocyanin of the crayfish Astacus leptodactylus and the snail Helix pomatia.

Authors:  D Van Hoof; R Witters; R Lontie
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

  2 in total

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