Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A unique mechanism regulating gene expression: translational inhibition by a complementary RNA transcript (micRNA).

Literature DB >> 6201848

A unique mechanism regulating gene expression: translational inhibition by a complementary RNA transcript (micRNA).

Abstract

The expression of the genes for the major outer membrane proteins OmpF and OmpC are osmoregulated. The ompC locus was found to be transcribed bidirectionally under conditions of high osmolarity and a 174-base transcript encoded upstream of ompC was found to inhibit the OmpF production and to substantially reduce the amount of the ompF mRNA. This RNA [mRNA-interfering complementary RNA (micRNA)] has a long sequence that is complementary to the 5' end region of the ompF mRNA. We propose that the micRNA inhibits the translation of the ompF mRNA by hybridizing with it. This RNA interaction may cause premature termination of the transcription of the ompF gene or destabilization of the ompF mRNA or both.

Mesh：

Substances：

Year: 1984 PMID： 6201848 PMCID： PMC345417 DOI： 10.1073/pnas.81.7.1966

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

27 in total

1. Sequences at the somatic recombination sites of immunoglobulin light-chain genes.

Authors: H Sakano; K Hüppi; G Heinrich; S Tonegawa
Journal: Nature Date: 1979-07-26 Impact factor: 49.962

2. Spliced early mRNAs of simian virus 40.

Authors: A J Berk; P A Sharp
Journal: Proc Natl Acad Sci U S A Date: 1978-03 Impact factor: 11.205

Review 3. Cyclic adenosine 5'-monophosphate in Escherichia coli.

Authors: I Pastan; S Adhya
Journal: Bacteriol Rev Date: 1976-09

Review 4. Control of transcription termination.

Authors: S Adhya; M Gottesman
Journal: Annu Rev Biochem Date: 1978 Impact factor: 23.643

5. Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli.

Authors: W V Alphen; B Lugtenberg
Journal: J Bacteriol Date: 1977-08 Impact factor: 3.490

6. A mutation which changes a membrane protein of E. coli.

Authors: M Inouye; J P Guthrie
Journal: Proc Natl Acad Sci U S A Date: 1969-11 Impact factor: 11.205

7. Processing of mRNA by ribonuclease III regulates expression of gene 1.2 of bacteriophage T7.

Authors: H Saito; C C Richardson
Journal: Cell Date: 1981-12 Impact factor: 41.582

8. Separation and characterization of the outer membrane of Pseudomonas aeruginosa.

Authors: T Mizuno; M Kageyama
Journal: J Biochem Date: 1978-07 Impact factor: 3.387

9. Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels.

Authors: N Rave; R Crkvenjakov; H Boedtker
Journal: Nucleic Acids Res Date: 1979-08-10 Impact factor: 16.971

10. Influence of molecular size and osmolarity of sugars and dextrans on the synthesis of outer membrane proteins O-8 and O-9 of Escherichia coli K-12.

Authors: H Kawaji; T Mizuno; S Mizushima
Journal: J Bacteriol Date: 1979-12 Impact factor: 3.490

250 in total

1. Activation of multiple antibiotic resistance in uropathogenic Escherichia coli strains by aryloxoalcanoic acid compounds.

Authors: C Balagué; E G Véscovi
Journal: Antimicrob Agents Chemother Date: 2001-06 Impact factor: 5.191

Review 9. Regulatory RNAs in bacteria.

Authors: Lauren S Waters; Gisela Storz
Journal: Cell Date: 2009-02-20 Impact factor: 41.582

10. Transcriptomic profiling of the oyster pathogen Vibrio splendidus opens a window on the evolutionary dynamics of the small RNA repertoire in the Vibrio genus.

Authors: Claire Toffano-Nioche; An N Nguyen; Claire Kuchly; Alban Ott; Daniel Gautheret; Philippe Bouloc; Annick Jacq
Journal: RNA Date: 2012-10-24 Impact factor: 4.942

A unique mechanism regulating gene expression: translational inhibition by a complementary RNA transcript (micRNA).

1. Sequences at the somatic recombination sites of immunoglobulin light-chain genes.

2. Spliced early mRNAs of simian virus 40.

Review 3. Cyclic adenosine 5'-monophosphate in Escherichia coli.

Review 4. Control of transcription termination.

5. Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli.

6. A mutation which changes a membrane protein of E. coli.

7. Processing of mRNA by ribonuclease III regulates expression of gene 1.2 of bacteriophage T7.

8. Separation and characterization of the outer membrane of Pseudomonas aeruginosa.

9. Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels.

10. Influence of molecular size and osmolarity of sugars and dextrans on the synthesis of outer membrane proteins O-8 and O-9 of Escherichia coli K-12.

1. Activation of multiple antibiotic resistance in uropathogenic Escherichia coli strains by aryloxoalcanoic acid compounds.

2. A plant virus satellite RNA exhibits a significant sequence complementarity to a chloroplast tRNA.

Review 3. Use of antisense RNA to confer bacteriophage resistance in dairy starter cultures.

Review 4. Structure and functional properties of prokaryotic small noncoding RNAs.

5. MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli.

6. Inhibition of specific gene expressions by protein-mediated mRNA interference.

7. Cloning of the gene encoding the major outer membrane protein of Haemophilus influenzae type b.

8. Translation inhibition from a distance: The small RNA SgrS silences a ribosomal protein S1-dependent enhancer.

Review 9. Regulatory RNAs in bacteria.

10. Transcriptomic profiling of the oyster pathogen Vibrio splendidus opens a window on the evolutionary dynamics of the small RNA repertoire in the Vibrio genus.