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Literature DB >> 6197628

Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene.

Abstract

Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro exposure to the carcinogen 3-methylcholanthrene. These oncogenes are now shown to be versions of the cellular Kirsten ras gene and are therefore homologous to oncogenes detected in a variety of human tumor DNAs.

Entities: Chemical Disease Species

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Year: 1983 PMID： 6197628 PMCID： PMC370101 DOI： 10.1128/mcb.3.12.2298-2301.1983

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

24 in total

1. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

2. Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

Authors: C Shih; B Z Shilo; M P Goldfarb; A Dannenberg; R A Weinberg
Journal: Proc Natl Acad Sci U S A Date: 1979-11 Impact factor: 11.205

3. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

Authors: C A Reznikoff; J S Bertram; D W Brankow; C Heidelberger
Journal: Cancer Res Date: 1973-12 Impact factor: 12.701

4. Three different human tumor cell lines contain different oncogenes.

Authors: M J Murray; B Z Shilo; C Shih; D Cowing; H W Hsu; R A Weinberg
Journal: Cell Date: 1981-08 Impact factor: 41.582

5. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes.

Authors: R W Ellis; D Defeo; T Y Shih; M A Gonda; H A Young; N Tsuchida; D R Lowy; E M Scolnick
Journal: Nature Date: 1981-08-06 Impact factor: 49.962

10. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse.

Authors: S H Reynolds; S J Stowers; R R Maronpot; M W Anderson; S A Aaronson
Journal: Proc Natl Acad Sci U S A Date: 1986-01 Impact factor: 11.205

Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene.

1. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

2. Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

3. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

4. Three different human tumor cell lines contain different oncogenes.

5. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes.

6. Unique transforming gene in carcinogen-transformed mouse cells.

7. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

8. Proposal for naming host cell-derived inserts in retrovirus genomes.

9. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene.

10. Partial transcription of murine type C viral genomes in BALB c cell lines.

Review 1. A brief history of melanoma: from mummies to mutations.

2. Increased radiation-induced transformation in C3H/10T1/2 cells after transfer of an exogenous c-myc gene.

3. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.

4. The in vivo clearance of Ha-ras transformants by natural killer cells.

5. Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver.

6. Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli.

7. Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins.

Review 8. Clinical relevance of KRAS in human cancers.

9. Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins.

10. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse.