Literature DB >> 6283357

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene.

L F Parada, C J Tabin, C Shih, R A Weinberg.   

Abstract

Examination of homologies between retroviral oncogenes and transforming sequences defined by transfection reveals that the human bladder carcinoma (EJ) oncogene is homologous to the Harvey sarcoma virus oncogene (ras). Structural analysis limits the region of homology to a 3.0-kilobase SacI fragment of the EJ oncogene. Both EJ and ras DNA probes detect similar transcripts in transfectants derived from bladder carcinoma cell lines.

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Year:  1982        PMID： 6283357     DOI： 10.1038/297474a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  240 in total

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