Literature DB >> 3550436

Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins.

A K Deshpande, H F Kung.   

Abstract

Microinjection of transforming p21 ras protein induces maturation of Xenopus laevis oocytes, and the induction is blocked by coinjection of monoclonal antibody (Y13-259) against p21 ras proteins. Similar to other inducing agents, the effect of p21 ras protein is mediated via the appearance of maturation or meiosis-promoting factor activity. In addition, the neutralizing antibody markedly reduces oocyte maturation after insulin induction, whereas it fails to inhibit progesterone induction. Our results suggest that insulin induces maturation of oocytes via a different pathway than that of steroidal agents. The induction by insulin is ras dependent, and the action of ras may be directed at the steps before meiosis-promoting factor autocatalytic activation. These results suggest a role of p21 ras protein in the events associated with amphibian oocyte maturation.

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Year:  1987        PMID： 3550436      PMCID： PMC365205          DOI： 10.1128/mcb.7.3.1285-1288.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  51 in total

1.  Ovarian progesterone levels during in vitro oocyte maturation and ovulation in Xenopus laevis.

Authors:  J E Fortune; P W Concannon; W Hansel
Journal:  Biol Reprod       Date:  1975-12       Impact factor: 4.285

2.  THE R OLE OF THE GERMINAL VESICLE IN OOECYTE MATURATION IN ANURANS AS REVEALED BY THE REMOVAL AND TRANSPLANTATION OF NUCLEI.

Authors:  T A DETTLAFF; L A NIKITINA; O G STROEVA
Journal:  J Embryol Exp Morphol       Date:  1964-12

3.  Studies on the appearance and nature of a maturation-inducing factor in the cytoplasm of amphibian oocytes exposed to progesterone.

Authors:  J K Reynhout; L D Smith
Journal:  Dev Biol       Date:  1974-06       Impact factor: 3.582

4.  Hormone-induced maturation of Xenopus laevis oocytes: effects of different steroids and study of the properties of a progesterone receptor.

Authors:  S Jacobelli; J Hanocq; E Baltus; J Brachet
Journal:  Differentiation       Date:  1974-06       Impact factor: 3.880

5.  Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals.

Authors:  J N Dumont
Journal:  J Morphol       Date:  1972-02       Impact factor: 1.804

6.  Progesterone induced maturation in oocytes of Xenopus laevis. Appearance of a 'maturation promoting factor' in enucleated oocytes.

Authors:  S Schorderet-Slatkine; K C Drury
Journal:  Cell Differ       Date:  1973-10

7.  Action of progesterone and related steroids on oocyte maturation in Xenopus laevis. An in vitro study.

Authors:  S Schorderet-Slatkine
Journal:  Cell Differ       Date:  1972-08

8.  A bioassay for progesterone and gonadotropins based on the meiotic division of Xenopus oocytes in vitro.

Authors:  V F Thornton
Journal:  Gen Comp Endocrinol       Date:  1971-06       Impact factor: 2.822

9.  Progesterone-induced maturational events in oocytes of Xenopus laevis. I. Continuous necessity for diffusible calcium and magnesium.

Authors:  R W Merriam
Journal:  Exp Cell Res       Date:  1971-09       Impact factor: 3.905

10.  Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.

Authors:  Y Masui; C L Markert
Journal:  J Exp Zool       Date:  1971-06
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  38 in total

1.  Comparison of molecular dynamics averaged structures for complexes of normal and oncogenic ras-p21 with SOS nucleotide exchange protein, containing computed conformations for three crystallographically undefined domains, suggests a potential role of these domains in ras signaling.

Authors:  Thomas Duncan; James M Chen; Fred K Friedman; Mark Hyde; Lyndon Chie; Matthew R Pincus
Journal:  Protein J       Date:  2004-04       Impact factor: 2.371

2.  Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling.

Authors:  Lyndon Chie; Fred K Friedman; Thomas Duncan; James M Chen; Denise Chung; Matthew Pincus
Journal:  Protein J       Date:  2004-04       Impact factor: 2.371

3.  Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

Authors:  D W Stacey; L A Feig; J B Gibbs
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

4.  H-ras(val12) induces cytoplasmic but not nuclear events of the cell cycle in small Xenopus oocytes.

Authors:  A D Johnson; R J Cork; M A Williams; K R Robinson; L D Smith
Journal:  Cell Regul       Date:  1990-06

5.  Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein.

Authors:  Lyndon Chie; Denise Chung; Matthew R Pincus
Journal:  Protein J       Date:  2005-05       Impact factor: 2.371

6.  Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins.

Authors:  Steven Smith; Mark Hyde; Matthew R Pincus
Journal:  Protein J       Date:  2005-08       Impact factor: 2.371

7.  Modulation of maturation and ribosomal protein S6 phosphorylation in Xenopus oocytes by microinjection of oncogenic ras protein and protein kinase C.

Authors:  T Kamata; H F Kung
Journal:  Mol Cell Biol       Date:  1990-03       Impact factor: 4.272

Review 8.  The biochemistry of ras p21.

Authors:  R J Grand; D Owen
Journal:  Biochem J       Date:  1991-11-01       Impact factor: 3.857

9.  In vitro tyrosine phosphorylation studies on RAS proteins and calmodulin suggest that polylysine-like basic peptides or domains may be involved in interactions between insulin receptor kinase and its substrate.

Authors:  Y Fujita-Yamaguchi; S Kathuria; Q Y Xu; J M McDonald; H Nakano; T Kamata
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

10.  Evidence that the ras oncogene-encoded p21 protein induces oocyte maturation via activation of protein kinase C.

Authors:  D L Chung; P W Brandt-Rauf; I B Weinstein; S Nishimura; Z Yamaizumi; R B Murphy; M R Pincus
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205
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