Literature DB >> 6188105

Unmethylated domains in vertebrate DNA.

D N Cooper, M H Taggart, A P Bird.   

Abstract

We have detected a fraction that is rich in unmethylated HpaII and HhaI sites by end-labelling HpaII fragments of chicken DNA. The fraction is not obvious when DNA fragments are stained with ethidium bromide as it amounts to less than 2% of the genome. The average frequency of sites for HpaII is over thirteen times greater in the unmethylated fraction than in total DNA. Partial digests indicate that the unmethylated sites are clustered in the genome. Similar unmethylated fractions were detected in six other vertebrates in both somatic and germ line DNA.

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Year:  1983        PMID： 6188105      PMCID： PMC325743          DOI： 10.1093/nar/11.3.647

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  28 in total

1.  Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.

Authors:  T Maniatis; A Jeffrey; H van deSande
Journal:  Biochemistry       Date:  1975-08-26       Impact factor: 3.162

2.  Unmethylated DNA in mouse L cells. I. DNA fibre autoradiography.

Authors:  H Molitor; D Drahovsky; A Wacker
Journal:  Biochim Biophys Acta       Date:  1976-04-15

3.  Specific DNA methylation sites in the vicinity of the chicken beta-globin genes.

Authors:  J D McGhee; G D Ginder
Journal:  Nature       Date:  1979-08-02       Impact factor: 49.962

4.  Methylation of DNA in developing sea urchin embryos.

Authors:  P Grippo; M Iaccarino; E Parisi; E Scarano
Journal:  J Mol Biol       Date:  1968-09-14       Impact factor: 5.469

5.  Analysis of calf-thymus satellite DNA: evidence for specific methylation of cytosine in C-G sequences.

Authors:  F Gautier; H Bünemann; L Grotjahn
Journal:  Eur J Biochem       Date:  1977-10-17

6.  Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis.

Authors:  A P Bird; E M Southern
Journal:  J Mol Biol       Date:  1978-01-05       Impact factor: 5.469

7.  MspI, an isoschizomer of hpaII which cleaves both unmethylated and methylated hpaII sites.

Authors:  C Waalwijk; R A Flavell
Journal:  Nucleic Acids Res       Date:  1978-09       Impact factor: 16.971

8.  Methylation of mouse liver DNA studied by means of the restriction enzymes msp I and hpa II.

Authors:  J Singer; J Roberts-Ems; A D Riggs
Journal:  Science       Date:  1979-03-09       Impact factor: 47.728

9.  The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. I. The AT-rich spacer.

Authors:  N V Fedoroff; D D Brown
Journal:  Cell       Date:  1978-04       Impact factor: 41.582

10.  The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. II. The GC-rich region.

Authors:  J R Miller; E M Cartwright; G G Brownlee; N V Fedoroff; D D Brown
Journal:  Cell       Date:  1978-04       Impact factor: 41.582
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  72 in total

1.  Cytosine methylation is not involved in the heterochromatization of the paternal genome of mealybug Planococcus citri.

Authors:  G Buglia; V Predazzi; M Ferraro
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

2.  Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis.

Authors:  Ozren Bogdanovic; Steven W Long; Simon J van Heeringen; Arie B Brinkman; Jose Luis Gómez-Skarmeta; Hendrik G Stunnenberg; Peter L Jones; Gert Jan C Veenstra
Journal:  Genome Res       Date:  2011-06-02       Impact factor: 9.043

3.  Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.

Authors:  B Hendrich; J Guy; B Ramsahoye; V A Wilson; A Bird
Journal:  Genes Dev       Date:  2001-03-15       Impact factor: 11.361

4.  Non-methylated islands in fish genomes are GC-poor.

Authors:  S Cross; P Kovarik; J Schmidtke; A Bird
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

5.  CpG island chromatin: a platform for gene regulation.

Authors:  Neil P Blackledge; Robert Klose
Journal:  Epigenetics       Date:  2011-02-01       Impact factor: 4.528

6.  Analysis of methylation and distribution of CpG sequences on human active and inactive X chromosomes by in situ nick translation.

Authors:  G Prantera; M Ferraro
Journal:  Chromosoma       Date:  1990-04       Impact factor: 4.316

7.  Rare de novo methylation within the transposable element activator (Ac) in transgenic tobacco plants.

Authors:  B Nelsen-Salz; H P Döring
Journal:  Mol Gen Genet       Date:  1990-08

8.  Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding.

Authors:  Lia Kallenberger; Rachel Erb; Lucie Kralickova; Andrea Patrignani; Esther Stöckli; Josef Jiricny
Journal:  Mol Cell Biol       Date:  2019-11-12       Impact factor: 4.272

Review 9.  CG methylation.

Authors:  Charles Vinson; Raghunath Chatterjee
Journal:  Epigenomics       Date:  2012-12       Impact factor: 4.778

10.  Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry.

Authors:  Jason L Herring; Daniel K Rogstad; Lawrence C Sowers
Journal:  Chem Res Toxicol       Date:  2009-06       Impact factor: 3.739
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