Literature DB >> 424726

Methylation of mouse liver DNA studied by means of the restriction enzymes msp I and hpa II.

J Singer, J Roberts-Ems, A D Riggs.   

Abstract

The restriction enzymes Hpa II and Msp I both recognize the sequence 5'-CCGG (C, cytosine; G, guanine). However, Hpa II cuts mouse liver DNA to fragments four times larger than does Msp I. The size of DNA cut by Msp I is close to that predicted from base composition and nearest neighbor analysis. The most probable explanation of these results is that in mouse the site 5'-CCGG is highly methylated.

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Year:  1979        PMID： 424726     DOI： 10.1126/science.424726

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  48 in total

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Authors:  Michael K Skinner
Journal:  Epigenetics       Date:  2011-07-01       Impact factor: 4.528

2.  Detection of a CpA methylase in an insect system: characterization and substrate specificity.

Authors:  C Devajyothi; V Brahmachari
Journal:  Mol Cell Biochem       Date:  1992-03-25       Impact factor: 3.396

3.  Comparative isoschizomer profiling of cytosine methylation: the HELP assay.

Authors:  Batbayar Khulan; Reid F Thompson; Kenny Ye; Melissa J Fazzari; Masako Suzuki; Edyta Stasiek; Maria E Figueroa; Jacob L Glass; Quan Chen; Cristina Montagna; Eli Hatchwell; Rebecca R Selzer; Todd A Richmond; Roland D Green; Ari Melnick; John M Greally
Journal:  Genome Res       Date:  2006-06-29       Impact factor: 9.043

4.  Methylation of chloroplast DNAs in the life cycle of Chlamydomonas.

Authors:  H D Royer; R Sager
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

5.  DNA variations in regenerated plants of pea (Pisum sativum L.).

Authors:  E Cecchini; L Natali; A Cavallini; M Durante
Journal:  Theor Appl Genet       Date:  1992-09       Impact factor: 5.699

6.  A DNA signal from the Thy-1 gene defines de novo methylation patterns in embryonic stem cells.

Authors:  M Szyf; G Tanigawa; P L McCarthy
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

7.  Liver-specific expression of a Qa-encoded class I gene is associated with DNA hypomethylation.

Authors:  C G Miyada; R B Wallace
Journal:  Mol Cell Biol       Date:  1986-01       Impact factor: 4.272

8.  A novel type of secondary modification of two CCGG residues in the human gamma delta beta-globin gene locus.

Authors:  L H van der Ploeg; J Groffen; R A Flavell
Journal:  Nucleic Acids Res       Date:  1980-10-24       Impact factor: 16.971

9.  DNA methylation and the frequency of CpG in animal DNA.

Authors:  A P Bird
Journal:  Nucleic Acids Res       Date:  1980-04-11       Impact factor: 16.971

10.  The 5'-cytosine in CCGG1 is methylated in two eukaryotic DNAs and Msp I is sensitive to methylation at this site.

Authors:  T W Sneider
Journal:  Nucleic Acids Res       Date:  1980-09-11       Impact factor: 16.971
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