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Literature DB >> 6128731

Rimorphin, a unique, naturally occurring [Leu]enkephalin-containing peptide found in association with dynorphin and alpha-neo-endorphin.

D L Kilpatrick, A Wahlstrom, H W Lahm, R Blacher, S Udenfriend.

Abstract

The tridecapeptide NH2-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-COOH has been purified from extracts of bovine posterior pituitary glands. This unique peptide, which has been given the name "rimorphin," is a major [Leu]enkephalin-containing peptide in all tissues examined that contain dynorphin and alpha-neo-endorphin. However, except for the initial hexapeptide sequence, it is structurally unrelated to the other two peptides.

Entities: Chemical Species

Mesh：

Substances：

Year: 1982 PMID： 6128731 PMCID： PMC347150 DOI： 10.1073/pnas.79.21.6480

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

24 in total

1. Automatic Monitoring of primary amines in preparative column effluents with fluorescamine.

Authors: P Böhlen; S Stein; J Stone; S Udenfriend
Journal: Anal Biochem Date: 1975-08 Impact factor: 3.365

2. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.

Authors: S Nakanishi; A Inoue; T Kita; M Nakamura; A C Chang; S N Cohen; S Numa
Journal: Nature Date: 1979-03-29 Impact factor: 49.962

3. Binding assay for opioid peptides with neuroblastoma x glioma hybrid cells: specificity of the receptor site.

Authors: L D Gerber; S Stein; M Rubinstein; J Wideman; S Udenfriend
Journal: Brain Res Date: 1978-07-28 Impact factor: 3.252

4. Amino acid analysis with fluorescamine at the picomole level.

Authors: S Stein; P Böhlen; J Stone; W Dairman; S Udenfriend
Journal: Arch Biochem Biophys Date: 1973-03 Impact factor: 4.013

5. Immunoreactive dynorphin in pituitary and brain.

Authors: A Goldstein; V E Ghazarossian
Journal: Proc Natl Acad Sci U S A Date: 1980-10 Impact factor: 11.205

6. A highly potent 3200-dalton adrenal opioid peptide that contains both a [Met]- and [Leu]enkephalin sequence.

Authors: D L Kilpatrick; T Taniguchi; B N Jones; A S Stern; J E Shively; J Hullihan; S Kimura; S Stein; S Udenfriend
Journal: Proc Natl Acad Sci U S A Date: 1981-05 Impact factor: 11.205

7. The complete amino acid sequence of alpha-neo-endorphin.

Authors: K Kangawa; N Minamino; N Chino; S Sakakibara; H Matsuo
Journal: Biochem Biophys Res Commun Date: 1981-04-15 Impact factor: 3.575

8. An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin.

Authors: R V Lewis; A S Stern; S Kimura; J Rossier; S Stein; S Udenfriend
Journal: Science Date: 1980-06-27 Impact factor: 47.728

9. Putative enkephalin precursors in bovine adrenal medulla.

Authors: R V Lewis; A S Stern; J Rossier; S Stein; S Udenfriend
Journal: Biochem Biophys Res Commun Date: 1979-08-13 Impact factor: 3.575

10. Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.

Authors: M W Hunkapiller; L E Hood
Journal: Biochemistry Date: 1978-05-30 Impact factor: 3.162

10 in total

Rimorphin, a unique, naturally occurring [Leu]enkephalin-containing peptide found in association with dynorphin and alpha-neo-endorphin.

1. Automatic Monitoring of primary amines in preparative column effluents with fluorescamine.

2. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.

3. Binding assay for opioid peptides with neuroblastoma x glioma hybrid cells: specificity of the receptor site.

4. Amino acid analysis with fluorescamine at the picomole level.

5. Immunoreactive dynorphin in pituitary and brain.

6. A highly potent 3200-dalton adrenal opioid peptide that contains both a [Met]- and [Leu]enkephalin sequence.

7. The complete amino acid sequence of alpha-neo-endorphin.

8. An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin.

9. Putative enkephalin precursors in bovine adrenal medulla.

10. Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography.

Review 1. Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides.

Review 2. The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.

3. Relative contents and concomitant release of prodynorphin/neoendorphin-derived peptides in rat hippocampus.

4. Pro-dynorphin peptides are found in the same neurons throughout rat brain: immunocytochemical study.

Review 5. Dynorphin--still an extraordinarily potent opioid peptide.

6. Dynorphin converting enzyme with unusual specificity from rat brain.

7. Sequence and expression of the rat prodynorphin gene.

8. Differential processing of prodynorphin and proenkephalin in specific regions of the rat brain.

Review 9. Dynorphin and its role in alcohol use disorder.

10. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain.