Literature DB >> 6091031

Codon usage can affect efficiency of translation of genes in Escherichia coli.

M Robinson, R Lilley, S Little, J S Emtage, G Yarranton, P Stephens, A Millican, M Eaton, G Humphreys.   

Abstract

By inserting synthetic oligonucleotides into a highly expressed gene in E. coli it has been shown that unfavourable codon usage can reduce the maximum translation rate of a protein. However, in the case of the codon used (AGG), a significant effect on translation was only seen at very high transcription rates from a gene containing multiple copies of the unfavourable codon.

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Year:  1984        PMID： 6091031      PMCID： PMC320107          DOI： 10.1093/nar/12.17.6663

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  23 in total

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Authors:  W Fiers; H Grosjean
Journal:  Nature       Date:  1979-01-25       Impact factor: 49.962

2.  Nucleotide sequence analysis of the chloramphenicol resistance transposon Tn9.

Authors:  N K Alton; D Vapnek
Journal:  Nature       Date:  1979 Dec 20-27       Impact factor: 49.962

3.  Primary structure of a chloramphenicol acetyltransferase specified by R plasmids.

Authors:  W V Shaw; L C Packman; B D Burleigh; A Dell; H R Morris; B S Hartley
Journal:  Nature       Date:  1979 Dec 20-27       Impact factor: 49.962

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Authors:  H W Boyer; D Roulland-Dussoix
Journal:  J Mol Biol       Date:  1969-05-14       Impact factor: 5.469

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Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

6.  Secondary structure of mRNA and efficiency of translation initiation.

Authors:  D Iserentant; W Fiers
Journal:  Gene       Date:  1980-04       Impact factor: 3.688

7.  Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli. IV. Further studies on the role of arginine transfer RNA repression of the enzymes of arginine biosynthesis.

Authors:  T F Celis; W K Maas
Journal:  J Mol Biol       Date:  1971-11-28       Impact factor: 5.469

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Authors:  F H Crick
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469

9.  Single turnover kinetic studies of guanosine triphosphate hydrolysis and peptide formation in the elongation factor Tu-dependent binding of aminoacyl-tRNA to Escherichia coli ribosomes.

Authors:  R C Thompson; D B Dix; J F Eccleston
Journal:  J Biol Chem       Date:  1980-12-10       Impact factor: 5.157

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  92 in total

1.  Sequestration of specific tRNA species cognate to the last sense codon of an overproduced gratuitous protein.

Authors:  J Menez; V Heurgué-Hamard; R H Buckingham
Journal:  Nucleic Acids Res       Date:  2000-12-01       Impact factor: 16.971

2.  Regularities of context-dependent codon bias in eukaryotic genes.

Authors:  Alexei Fedorov; Serge Saxonov; Walter Gilbert
Journal:  Nucleic Acids Res       Date:  2002-03-01       Impact factor: 16.971

3.  Optimizing doped libraries by using genetic algorithms.

Authors:  D Tomandl; A Schober; A Schwienhorst
Journal:  J Comput Aided Mol Des       Date:  1997-01       Impact factor: 3.686

4.  A Chlamydia-specific C-terminal region of the stress response regulator HrcA modulates its repressor activity.

Authors:  Allan L Chen; Adam C Wilson; Ming Tan
Journal:  J Bacteriol       Date:  2011-09-30       Impact factor: 3.490

5.  Avoidance of long mononucleotide repeats in codon pair usage.

Authors:  Tingting Gu; Shengjun Tan; Xiaoxi Gou; Hitoshi Araki; Dacheng Tian
Journal:  Genetics       Date:  2010-08-30       Impact factor: 4.562

6.  Relationship between protein synthesis and concentrations of charged and uncharged tRNATrp in Escherichia coli.

Authors:  M V Rojiani; H Jakubowski; E Goldman
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

7.  Nonrandom utilization of codon pairs in Escherichia coli.

Authors:  G A Gutman; G W Hatfield
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

8.  Codon replacement in the PGK1 gene of Saccharomyces cerevisiae: experimental approach to study the role of biased codon usage in gene expression.

Authors:  A Hoekema; R A Kastelein; M Vasser; H A de Boer
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

9.  Genetic organization and molecular analysis of the EcoVIII restriction-modification system of Escherichia coli E1585-68 and its comparison with isospecific homologs.

Authors:  Iwona Mruk; Tadeusz Kaczorowski
Journal:  Appl Environ Microbiol       Date:  2003-05       Impact factor: 4.792

10.  Codon usage in regulatory genes in Escherichia coli does not reflect selection for 'rare' codons.

Authors:  P M Sharp; W H Li
Journal:  Nucleic Acids Res       Date:  1986-10-10       Impact factor: 16.971
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