Literature DB >> 6088388

The locus for apolipoprotein CII is closely linked to the apolipoprotein E locus on chromosome 19 in man.

O Myklebost, S Rogne, B Olaisen, T Gedde-Dahl, H Prydz.   

Abstract

We have demonstrated close linkage between the genes for apolipoprotein E (apoE) and apolipoprotein CII (apoCII). Families segregating for apoE protein variants were screened for a DNA restriction fragment length polymorphism close to the apoCII gene by using an apoCII cDNA clone. The maximum lod score is 4.52 (sexes combined) at a recombination frequency of zero. Given linkage, it may be assumed that no recombinations have happened in altogether 33 observed meioses. It is therefore evident that the apoCII gene is situated on chromosome 19, close to the apoE gene.

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Year:  1984        PMID： 6088388     DOI： 10.1007/bf00291359

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  19 in total

1.  Sequential tests for the detection of linkage.

Authors:  N E MORTON
Journal:  Am J Hum Genet       Date:  1955-09       Impact factor: 11.025

2.  Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Authors:  L M Kunkel; K D Smith; S H Boyer; D S Borgaonkar; S S Wachtel; O J Miller; W R Breg; H W Jones; J M Rary
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  A specific apoprotein activator for lipoprotein lipase.

Authors:  J C LaRosa; R I Levy; P Herbert; S E Lux; D S Fredrickson
Journal:  Biochem Biophys Res Commun       Date:  1970-10-09       Impact factor: 3.575

Review 4.  Report of the Committee on Human Gene Mapping by Recombinant DNA Techniques.

Authors:  M H Skolnick; H F Willard; L A Menlove
Journal:  Cytogenet Cell Genet       Date:  1984

Review 5.  Report of the Committee on the Genetic Constitution of Chromosomes 10, 11, and 12.

Authors:  P S Gerald; K H Grzeschik
Journal:  Cytogenet Cell Genet       Date:  1984

6.  The isolation and characterization of cDNA clones for human apolipoprotein CII.

Authors:  O Myklebost; B Williamson; A F Markham; S R Myklebost; J Rogers; D E Woods; S E Humphries
Journal:  J Biol Chem       Date:  1984-04-10       Impact factor: 5.157

7.  Familial apolipoprotein CII deficiency: plasma lipoproteins and apolipoproteins in heterozygous and homozygous subjects and the effects of plasma infusion.

Authors:  N E Miller; S N Rao; P Alaupovic; N Noble; J Slack; J D Brunzell; B Lewis
Journal:  Eur J Clin Invest       Date:  1981-02       Impact factor: 4.686

8.  Complement loci of the HLA complex. Studies on families with intra-HLA crossovers and haplotype associations.

Authors:  B Olaisen; P Teisberg; R Jonassen; T Gedde-Dahl; T Moen; E Thorsby
Journal:  Hum Immunol       Date:  1981-05       Impact factor: 2.850

9.  The locus for apolipoprotein E (apoE) is linked to the complement component C3 (C3) locus on chromosome 19 in man.

Authors:  B Olaisen; P Teisberg; T Gedde-Dahl
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

10.  Hypertriglyceridemia associated with deficiency of apolipoprotein C-II.

Authors:  W C Breckenridge; J A Little; G Steiner; A Chow; M Poapst
Journal:  N Engl J Med       Date:  1978-06-08       Impact factor: 91.245
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  19 in total

1.  Association analysis of lipid levels and apolipoprotein restriction fragment length polymorphisms.

Authors:  O Myklebost; S Rogne; I Hjermann; B Olaisen; H Prydz
Journal:  Hum Genet       Date:  1990-12       Impact factor: 4.132

Review 2.  Gene mapping and chromosome 19.

Authors:  D J Shaw; J D Brook; A L Meredith; H G Harley; M Sarfarazi; P S Harper
Journal:  J Med Genet       Date:  1986-02       Impact factor: 6.318

3.  Haplotypes identified by DNA polymorphisms at the apolipoprotein A-1 and C-III loci and hypertriglyceridaemia. A study in a Japanese population.

Authors:  A Rees; J Stocks; H Paul; Y Ohuchi; D Galton
Journal:  Hum Genet       Date:  1986-02       Impact factor: 4.132

4.  A physical map of the apolipoprotein gene cluster on human chromosome 19.

Authors:  O Myklebost; S Rogne
Journal:  Hum Genet       Date:  1988-03       Impact factor: 4.132

5.  Isolation and characterisation of a cDNA clone for human apolipoprotein CI and assignment of the gene to chromosome 19.

Authors:  F Tata; I Henry; A F Markham; S C Wallis; D Weil; K H Grzeschik; C Junien; R Williamson; S E Humphries
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

6.  Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes.

Authors:  V Lindgren; K L Luskey; D W Russell; U Francke
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

7.  A common restriction fragment length polymorphism of the human apolipoprotein E gene and its relationship to type III hyperlipidaemia.

Authors:  E C Klasen; P J Talmud; L Havekes; E de Wit; E van der Kooij-Meijs; M Smit; G Hansson; S E Humphries
Journal:  Hum Genet       Date:  1987-03       Impact factor: 4.132

8.  Tight linkage between myotonic dystrophy and apolipoprotein E genes revealed with allele-specific oligonucleotides.

Authors:  B Smeets; J Poddighe; H Brunner; H H Ropers; B Wieringa
Journal:  Hum Genet       Date:  1988-09       Impact factor: 4.132

9.  Linkage relationships of the gene for apolipoprotein CII with loci on chromosome 19.

Authors:  J A Donald; S C Wallis; A Kessling; P Tippett; E B Robson; S Ball; K E Davies; P Scambler; K Berg; A Heiberg
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 10.  Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review.

Authors:  Inga Kuhlmann; Anne Marie Minihane; Patricia Huebbe; Almut Nebel; Gerald Rimbach
Journal:  Lipids Health Dis       Date:  2010-01-28       Impact factor: 3.876
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