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Literature DB >> 5454145

Synaptic potentials recorded in cell cultures of nerve and muscle.

Abstract

Initially dissociated spinal cord and muscle cells derived from chick embryos differentiate sufficiently in tissue culture to form functional synaptic contacts. Spontaneous and evoked potentials recorded with intracellular microelectrodes resemble synaptic responses of adult spinal cord and neuromuscular junctions.

Entities: Species

Mesh：

Year: 1970 PMID： 5454145 DOI： 10.1126/science.169.3952.1331

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

17 in total

1. Synthesis of acetylcholine receptors by cultured chick myotubes and denervated mouse extensor digitorum longus muscles.

Authors: P N Devreotes; D M Fambrough
Journal: Proc Natl Acad Sci U S A Date: 1976-01 Impact factor: 11.205

2. Expression of an intrinsic growth strategy by mammalian retinal neurons.

Authors: P R Montague; M J Friedlander
Journal: Proc Natl Acad Sci U S A Date: 1989-09 Impact factor: 11.205

3. An ultrastructural and electrophysiological study of the development of neuro-muscular junctions between previously dissociated foetal rat cells in vitro.

Authors: M M Bird; D W James
Journal: Cell Tissue Res Date: 1974 Impact factor: 5.249

Synaptic potentials recorded in cell cultures of nerve and muscle.

1. Synthesis of acetylcholine receptors by cultured chick myotubes and denervated mouse extensor digitorum longus muscles.

2. Expression of an intrinsic growth strategy by mammalian retinal neurons.

3. An ultrastructural and electrophysiological study of the development of neuro-muscular junctions between previously dissociated foetal rat cells in vitro.

4. The effect of receptor desensitization on the action of alpha-bungaro-toxin on cultured skeletal muscle.

5. Acetylcholine receptors of muscle grown in vitro.

6. Synaptic differentiation in a regenerating crab-limb muscle.

7. A physiological study of chick myotubes grown in tissue culture.

Review 8. Microfabricated mammalian organ systems and their integration into models of whole animals and humans.

9. Isolation and culture of motoneurons from embryonic chicken spinal cords.

10. Methylxanthine-induced escalation: a propagated wave phenomenon observed in skeletal muscle developing in culture.