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Literature DB >> 5373676

Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.

Abstract

Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of (14)C-labeled luteoskyrin was 2-(14)C-malonate.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1969 PMID： 5373676 PMCID： PMC377994 DOI： 10.1128/am.18.3.406-409.1969

Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919

9 in total

1. MITOCHONDRIAL RESPIRATORY IMPAIRMENT BY LUTEOSKYRIN, A HEPATOTOXIC PIGMENT OF PENICILLIUM ISLANDICUM SOPP.

Authors: I UENO; Y UENO; T TATSUNO; K URAGUCHI
Journal: Jpn J Exp Med Date: 1964-06

2. [THE EFFECTS OF LUTEOSKYRIN, TOXIC SUBSTANCE FROM PENICILLIUM ISLANDICUM SOPP, ON THE SWELLING OF MITOCHONDRIA].

Authors: Y UENO; I UENO; T TATSUNO; K URAGUCHI
Journal: Jpn J Exp Med Date: 1964-08

3. CYTOTOXIC EFFECTS OF THE MYCOTOXINS OF PENICILLIUM ISLANDICUM SOPP, LUTEOSKYRIN AND CHLORINE-CONTAINING PEPTIDE ON CHANG'S LIVER CELLS AND HELA CELLS.

Authors: M UMEDA
Journal: Acta Pathol Jpn Date: 1964-08

4. Metabolic products of fungi. X. The structure of rubroskyrin and its relation to the structure of luteoskyrin.

Authors: I KITAGAWA; S SHIBATA
Journal: Pharm Bull Date: 1956-08

5. The mode of binding of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp, to deoxyribonucleic acid.

Authors: Y Ueno; I Ueno; K Mizumoto
Journal: Jpn J Exp Med Date: 1968-02

6. Inhibitory effects of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp, and chemically related pigments on a protozoon, Tetrahymena pyriformis GL.

Authors: Y Ueno; M Saheki
Journal: Jpn J Exp Med Date: 1968-06

7. The binding of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum sopp, to deoxyribonucleohistone.

Authors: Y Ueno; I Ueno; K Mizumoto; T Tatsuno
Journal: J Biochem Date: 1968-03 Impact factor: 3.387

8. [Interactions between pigments and nucleic acids. 4. Specific and non specific complexes between luteoskyrine, magnesium ions, and nucleic acids].

Authors: Y Ohba; P Fromageot
Journal: Eur J Biochem Date: 1967-04

9. Impairments of RNA synthesis in Ehrlich ascites tumour by luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp.

Authors: Y Ueno; I Ueno; K Ito; T Tatsuno
Journal: Experientia Date: 1967-12-15

9 in total

10 in total

1. Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H.

Authors: F Tashiro; K Hiral; Y Ueno
Journal: Appl Environ Microbiol Date: 1979-08 Impact factor: 4.792

Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.

1. MITOCHONDRIAL RESPIRATORY IMPAIRMENT BY LUTEOSKYRIN, A HEPATOTOXIC PIGMENT OF PENICILLIUM ISLANDICUM SOPP.

2. [THE EFFECTS OF LUTEOSKYRIN, TOXIC SUBSTANCE FROM PENICILLIUM ISLANDICUM SOPP, ON THE SWELLING OF MITOCHONDRIA].

3. CYTOTOXIC EFFECTS OF THE MYCOTOXINS OF PENICILLIUM ISLANDICUM SOPP, LUTEOSKYRIN AND CHLORINE-CONTAINING PEPTIDE ON CHANG'S LIVER CELLS AND HELA CELLS.

4. Metabolic products of fungi. X. The structure of rubroskyrin and its relation to the structure of luteoskyrin.

5. The mode of binding of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp, to deoxyribonucleic acid.

6. Inhibitory effects of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp, and chemically related pigments on a protozoon, Tetrahymena pyriformis GL.

7. The binding of luteoskyrin, a hepatotoxic pigment of Penicillium islandicum sopp, to deoxyribonucleohistone.

8. [Interactions between pigments and nucleic acids. 4. Specific and non specific complexes between luteoskyrine, magnesium ions, and nucleic acids].

9. Impairments of RNA synthesis in Ehrlich ascites tumour by luteoskyrin, a hepatotoxic pigment of Penicillium islandicum Sopp.

1. Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H.

2. Polyphasic taxonomy of the genus Talaromyces.

3. Detection of mycotoxins by thin-layer chromatography: application to screening of fungal extracts.

4. Simple screening method for molds producing intracellular mycotoxins in pure cultures.

5. Production of the hepatotoxic chlorine-containing peptide by Penicillium islandicum Sopp.

6. Effects of mycotoxins on the mixed lymphocyte reaction.

7. Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.

Review 8. Mycotoxins: toxicity, carcinogenicity, and the influence of various nutritional conditions.

9. Taxonomic re-evaluation of species in Talaromyces section Islandici, using a polyphasic approach.

10. New section and species in Talaromyces.