Literature DB >> 565188

Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.

A C Ghosh, A Manmade, B Kobbe, J M Townsend, A L Demain.   

Abstract

Production of luteoskyrin, a hepatotoxin synthesized by Penicillium islandicum Sopp., was studied with various fermentation methods. Best results were obtained in static fermentations on glutinous rice at 30 degrees C. The isolated yield of pure luteoskyrin was approximately 400 mg per kg of rice. Also produced were skyrin, islandicin, iridoskyrin, rubroskyrin, chrysophanol, mannitol, and erythritol. A new metabolite, which we call pibasterol, was also isolated.

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Year:  1978        PMID: 565188      PMCID: PMC242880          DOI: 10.1128/aem.35.3.563-566.1978

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  10 in total

Review 1.  Mycotoxins.

Authors:  G N Wogan
Journal:  Annu Rev Pharmacol       Date:  1975       Impact factor: 13.820

2.  MITOCHONDRIAL RESPIRATORY IMPAIRMENT BY LUTEOSKYRIN, A HEPATOTOXIC PIGMENT OF PENICILLIUM ISLANDICUM SOPP.

Authors:  I UENO; Y UENO; T TATSUNO; K URAGUCHI
Journal:  Jpn J Exp Med       Date:  1964-06

3.  Isolation of two toxic agents, luteoskyrin and chlorine-containing peptide, from the metabolites of Penicillium islandicum Sopp, with some properties thereof.

Authors:  K URAGUCHI
Journal:  Jpn J Exp Med       Date:  1961-02

4.  [Study of the toxic principle in yellow rice].

Authors:  T TATSUNO; M TSUKIOKA; Y SAKAI; Y SUZUKI; Y ASAMI
Journal:  Pharm Bull       Date:  1955-12

5.  Isolation and characterization of luteoskyrin and rugulosin, two hepatotoxic anthraquinonoids from Penicillium islandicum Sopp. and Penicillium rugulosum Thom.

Authors:  J C Bouhet; P P Van Chuong; F Toma; M Kirszenbaum; P Fromageot
Journal:  J Agric Food Chem       Date:  1976 Sep-Oct       Impact factor: 5.279

6.  Microbial assay of hepatotoxic anthraquinones with Escherichia coli F-11.

Authors:  H Yamakawa; Y Ueno
Journal:  Chem Pharm Bull (Tokyo)       Date:  1970-01       Impact factor: 1.645

7.  Some recent studies on the metabolites of fungi and lichens.

Authors:  S Shibata
Journal:  Pure Appl Chem       Date:  1973       Impact factor: 2.453

8.  Biotechnology report. Solid state fermentations.

Authors:  C W Hesseltine
Journal:  Biotechnol Bioeng       Date:  1972-07       Impact factor: 4.530

9.  The bioassay of aflatoxins and related substances with Bacillus megaterium spores and chick embryos.

Authors:  A Jayaraman; E J Herbst; M Ikawa
Journal:  J Am Oil Chem Soc       Date:  1968-10       Impact factor: 1.849

10.  Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.

Authors:  Y Ueno; I Ishikawa
Journal:  Appl Microbiol       Date:  1969-09
  10 in total
  6 in total

1.  Polyphasic taxonomy of the genus Talaromyces.

Authors:  N Yilmaz; C M Visagie; J Houbraken; J C Frisvad; R A Samson
Journal:  Stud Mycol       Date:  2014-06       Impact factor: 16.097

2.  Plate diffusion assay as a rapid method for dosimetry of mutagens.

Authors:  T E Awerbuch; A A Stark
Journal:  Appl Environ Microbiol       Date:  1979-12       Impact factor: 4.792

3.  Toxicity of metabolites from Rhizopus spp.

Authors:  D P Thompson; B E Eribo; A W Smalley
Journal:  Bull Environ Contam Toxicol       Date:  1982-05       Impact factor: 2.151

4.  Production of cyclochlorotine and a new metabolite, simatoxin, by Penicillium islandicum Sopp.

Authors:  A C Ghosh; A Manmade; J M Townsend; A Bousquet; J F Howes; A L Demain
Journal:  Appl Environ Microbiol       Date:  1978-06       Impact factor: 4.792

5.  Mutagenicity of islandicin and chrysophanol in the Salmonella/microsome system.

Authors:  D F Liberman; F L Schaefer; R C Fink; M Ramgopal; A C Ghosh; R Mulcahy
Journal:  Appl Environ Microbiol       Date:  1980-09       Impact factor: 4.792

Review 6.  Chrysophanol: A Natural Anthraquinone with Multifaceted Biotherapeutic Potential.

Authors:  Mohd Aslam Yusuf; Brahma N Singh; Surya Sudheer; Ravindra N Kharwar; Saba Siddiqui; Ahmed M Abdel-Azeem; Leonardo Fernandes Fraceto; Kavya Dashora; Vijai K Gupta
Journal:  Biomolecules       Date:  2019-02-18
  6 in total

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